AI Article Synopsis

  • Raman spectroscopy provides non-destructive, real-time analysis of living cells and tissues by measuring scattered light, offering insights into their molecular structure and composition.
  • The technique produces a "molecular fingerprint" that helps link specific cellular and tissue compositions to various disease states, aiding in the early detection of diseases.
  • By identifying predisease conditions—when a healthy state shifts toward disease—Raman spectroscopy could play a vital role in preventing disease onset through insights into biological processes and molecular dynamics.

Article Abstract

Raman spectroscopy shows great potential for practical clinical applications. By analyzing the structure and composition of molecules through real-time, non-destructive measurements of the scattered light from living cells and tissues, it offers valuable insights. The Raman spectral data directly link to the molecular composition of the cells and tissues and provides a "molecular fingerprint" for various disease states. This review focuses on the practical and clinical applications of Raman spectroscopy, especially in the early detection of human diseases. Identifying predisease, which marks the transition from a healthy to a disease state, is crucial for effective interventions to prevent disease onset. Raman spectroscopy can reveal biological processes occurring during the transition states and may eventually detect the molecular dynamics in predisease conditions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418989PMC
http://dx.doi.org/10.3390/ijms241512170DOI Listing

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