AI Article Synopsis
- Chitosan films were created using an acetic acid solution, which composed 15.49% of the final mixture.
- These films demonstrated compatibility with human skin cells (HaCaT) and exhibited strong antiviral properties, effectively inactivating up to 99.98% of certain enveloped viruses and 99.92% of non-enveloped viruses.
- The study suggests that these biodegradable chitosan/acetic acid films could be valuable for medical uses where antiviral materials are needed.
Article Abstract
Chitosan films were prepared by solvent casting using an acetic acid-based solution. The films that were developed contained 15.49% of acetic acid solution (10% /) and showed biocompatibility in vitro in human keratinocyte HaCaT cells and potent antiviral activity against both enveloped and non-enveloped viruses. The results showed up to 99.98% and 99.92% viral inactivation against the phi 6 enveloped bacteriophage and MS2 non-enveloped bacteriophage, respectively, suggesting that this chitosan/acetic acid film is a promising material for biomedical applications that require biodegradable broad-spectrum antiviral materials.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10418510 | PMC |
| http://dx.doi.org/10.3390/ijms241512028 | DOI Listing |
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