Manuka honey plays a significant role in modern medical applications as an antibacterial, antiviral, and antibiotic agent. However, although the importance of manuka honey is well documented in the literature, information regarding its physicochemical characteristics remains limited. Moreover, so far, only a few papers address this issue in conjunction with the examination of the pollen composition of manuka honey samples. Therefore, in this study, two parameters crucial for honey quality control-the diastase number (DN) and the hydroxymethylfurfural (HMF) content-as well as the melissopalynological analysis of manuka honey, were examined. The research found a large variation in the percentage of pollen in honeys labeled and sold as manuka honeys. Furthermore, a significant proportion of these honeys was characterized by a low DN. However, since low diastase activity was not associated with low HMF content, manuka honey should not be considered as a honey with naturally low enzymatic activity. Overall, the DN and HMF content results indicate that the quality of commercially available manuka honey is questionable.
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http://dx.doi.org/10.3390/foods12152930 | DOI Listing |
Nutrients
January 2025
Orthodontics, Department of Conservative Odontology, Faculty of Dental Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Unlabelled: Honey is abundant in bioactive compounds, which demonstrate considerable therapeutic effects, particularly on oxidative stress and inflammation.
Objectives: This work sought to evaluate the antioxidant mechanisms of Manuka honey (MH) and Ohia Lehua honey (OLH), correlating them with phytochemical analyses in a rat model of experimentally induced inflammation.
Methods: The identification of polyphenolic compounds in the extracts was carried out using HPLC-ESI MS.
Antibiotics (Basel)
December 2024
Nanomedicine Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia.
The emergence of multidrug-resistant bacteria presents a significant global health threat. Liposomal antibiotics have shown a potential to improve antibiotic delivery and efficacy. This study aimed to develop liposomes encapsulating tobramycin (TOB) and methylglyoxal (MGO) to enhance TOB activity while reducing bacterial adhesion and biofilm formation.
View Article and Find Full Text PDFJ Agric Food Chem
January 2025
Faculty of Health and Nutrition, Shubun University, Ichinomiya, Aichi 491-0938, Japan.
Leptosperin (methyl syringate-4--β-d-gentiobioside) serves as a unique marker for ma̅nuka honey, derived from the ma̅nuka plant (). Despite its importance, the biosynthesis pathway of leptosperin remains unreported. This study investigates the molecular mechanism of leptosperin formation from its aglycone, methyl syringate (MSYR), in ma̅nuka plants.
View Article and Find Full Text PDFFront Vet Sci
January 2025
College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States.
Veterinary intervention in zoological species can be complicated by species-specific social dynamics. African wild dogs are a pack species and removal or separation of an individual may disrupt established pack hierarchy resulting in conspecific aggression. Therefore, medical interventions that optimize a quick return to health are ideal to minimize the duration of absence from the pack.
View Article and Find Full Text PDFWound Manag Prev
December 2024
Acute Surgical Wound Service, Department of Surgery, Christiana Care, Newark, DE; Department of Surgery, Christiana Care, Newark, DE.
Background: Traumatic injuries have increased risks for infection and progression to difficult-to-heal wounds. Often, they are inadequately treated with single-purpose dressings. Involving wound care specialists allows for integrating various advanced wound treatments.
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