Computed tomography (CT) scans, or radiographic images, were used to aid in the early diagnosis of patients and detect normal and abnormal lung function in the human chest. However, the diagnosis of lungs infected with coronavirus disease 2019 (COVID-19) was made more accurately from CT scan data than from a swab test. This study uses human chest radiography pictures to identify and categorize normal lungs, lung opacities, COVID-19-infected lungs, and viral pneumonia (often called pneumonia). In the past, several CAD systems using image processing, ML/DL, and other forms of machine learning have been developed. However, those CAD systems did not provide a general solution, required huge hyper-parameters, and were computationally inefficient to process huge datasets. Moreover, the DL models required high computational complexity, which requires a huge memory cost, and the complexity of the experimental materials' backgrounds, which makes it difficult to train an efficient model. To address these issues, we developed the Inception module, which was improved to recognize and detect four classes of Chest X-ray in this research by substituting the original convolutions with an architecture based on modified-Xception (m-Xception). In addition, the model incorporates depth-separable convolution layers within the convolution layer, interlinked by linear residuals. The model's training utilized a two-stage transfer learning process to produce an effective model. Finally, we used the XgBoost classifier to recognize multiple classes of chest X-rays. To evaluate the m-Xception model, the 1095 dataset was converted using a data augmentation technique into 48,000 X-ray images, including 12,000 normal, 12,000 pneumonia, 12,000 COVID-19 images, and 12,000 lung opacity images. To balance these classes, we used a data augmentation technique. Using public datasets with three distinct train-test divisions (80-20%, 70-30%, and 60-40%) to evaluate our work, we attained an average of 96.5% accuracy, 96% F1 score, 96% recall, and 96% precision. A comparative analysis demonstrates that the m-Xception method outperforms comparable existing methods. The results of the experiments indicate that the proposed approach is intended to assist radiologists in better diagnosing different lung diseases.
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http://dx.doi.org/10.3390/diagnostics13152583 | DOI Listing |
Sleep Health
January 2025
Department of Human and Development and Family Studies, Pennsylvania State University, University Park, Pennsylvania, USA.
Goal And Aims: One challenge using wearable sensors is nonwear time. Without a nonwear (e.g.
View Article and Find Full Text PDFAcad Radiol
January 2025
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China (Y.X., B.X., Z.W., C.P., M.X.). Electronic address:
Rationale And Objectives: To develop and externally validate interpretable CT radiomics-based machine learning (ML) models for preoperative Ki-67 expression prediction in clear cell renal cell carcinoma (ccRCC).
Methods: 506 patients were retrospectively enrolled from three independent institutes and divided into the training (n=357) and external test (n=149) sets. Ki67 expression was determined by immunohistochemistry (IHC) and categorized into low (<15%) and high (≥15%) expression groups.
Comput Methods Programs Biomed
December 2024
Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milano, MI, 20133, Italy. Electronic address:
Background And Objective: Helmet-Continuous Positive Airway Pressure (H-CPAP) is a non-invasive respiratory support that is used for the treatment of Acute Respiratory Distress Syndrome (ARDS), a severe medical condition diagnosed when symptoms like profound hypoxemia, pulmonary opacities on radiography, or unexplained respiratory failure are present. It can be classified as mild, moderate or severe. H-CPAP therapy is recommended as the initial treatment approach for mild ARDS.
View Article and Find Full Text PDFPLoS One
January 2025
Institute for Physical Activity and Nutrition, Deakin University, Melbourne, VIC, Australia.
Heart disease remains a leading cause of mortality and morbidity worldwide, necessitating the development of accurate and reliable predictive models to facilitate early detection and intervention. While state of the art work has focused on various machine learning approaches for predicting heart disease, but they could not able to achieve remarkable accuracy. In response to this need, we applied nine machine learning algorithms XGBoost, logistic regression, decision tree, random forest, k-nearest neighbors (KNN), support vector machine (SVM), gaussian naïve bayes (NB gaussian), adaptive boosting, and linear regression to predict heart disease based on a range of physiological indicators.
View Article and Find Full Text PDFBiol Direct
January 2025
Cancer Research Center Nantong, Affiliated Tumor Hospital of Nantong University & Nantong Tumor Hospital, Nantong, China.
Background: Endothelial cells are integral components of the tumor microenvironment and play a multifaceted role in tumor immunotherapy. Targeting endothelial cells and related signaling pathways can improve the effectiveness of immunotherapy by normalizing tumor blood vessels and promoting immune cell infiltration. However, to date, there have been no comprehensive studies analyzing the role of endothelial cells in the diagnosis and treatment of prostate adenocarcinoma (PRAD).
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