Purpose Of Review: Sarcopenic obesity (SO) is a growing public health problem in older adults. Whether SO confers higher risk of cardiometabolic disease and mortality than obesity or sarcopenia alone is still a matter of debate. We focus on recent findings on SO and cardiometabolic health and mortality in older adults.
Recent Findings: SO is associated with increased mortality compared to non-sarcopenic obesity, but similar mortality risk compared to sarcopenia without obesity. SO is associated with a higher risk of cardiovascular disease (CVD), diabetes, and physical disability than obesity or sarcopenia alone. SO, in the presence of diabetes, is associated with the highest risk of CVD and chronic kidney disease. A definition and diagnostic criteria for SO has recently been proposed (ESPEN and EASO). SO is associated with more adverse outcomes overall than sarcopenia or obesity alone. Future research is required to assess the impact of the new SO definition on health outcomes.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10640508 | PMC |
http://dx.doi.org/10.1007/s11892-023-01522-2 | DOI Listing |
Curr Issues Mol Biol
November 2024
Department of Biochemistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Obesity causes fat accumulation, and sarcopenia causes loss of muscle mass and strength; together, they worsen insulin resistance and accelerate muscle decline, creating a harmful cycle. Some supplements, along with physical exercise, could be remedies for sarcopenic obesity (SO). In this review, we aim to draw a comparison between supplements studied in experimental research and those evaluated in clinical studies for SO.
View Article and Find Full Text PDFWorld J Surg
December 2024
Department of Gastroenterological Surgery, Cancer Institute Ariake Hospital, Tokyo, Japan.
Background: We elucidated the influence of sarcopenic obesity on postoperative outcomes in patients with oesophago-gastric cancer.
Methods: We conducted a systematic search on MEDLINE, the Cochrane Central Register of Controlled Trials, EMBASE, the World Health Organization International Clinical Trials Platform Search Portal, and ClinicalTrials.gov to identify observational studies published from their inception to September 26, 2024.
Age Ageing
November 2024
Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain.
J Neurosurg Spine
December 2024
1Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts; and.
Objective: The prognostic significance of body composition phenotypes for survival in patients undergoing surgical intervention for spinal metastases has not yet been elucidated. This study aimed to elucidate the impact of body composition phenotypes on surgical outcomes and 5-year survival.
Methods: The records of patients treated surgically for spinal metastases between 2010 and 2020 were retrospectively evaluated.
Br J Nutr
December 2024
Department of Radiation Oncology, School of Medicine, Koc University, Istanbul, Turkey.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!