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Article Synopsis
  • The study aimed to assess the effectiveness of primary angioplasty by measuring TIMI flow and myocardial blush grades (MBG) before and after the procedure.
  • Conducted on 106 patients at the Punjab Institute of Cardiology, the study found that 65% showed improved TIMI flow and 55% improved MBG, with quicker balloon insertion time linked to better outcomes.
  • The conclusion highlights that while primary angioplasty is effective for restoring blood flow in heart attacks, there is still room for improvement, especially for patients presenting late.
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Background: To analyze the effects on coagulation function and safety of bivalirudin and heparin in patients undergoing percutaneous coronary intervention (PCI) and provide clinical evidence for their application.

Methods: A total of 42 patients with coronary heart disease undergoing PCI treatment from July 2019 to January 2022 at Datong Third People's Hospital in China were divided into 2 groups: the bivalirudin group and the heparin group. The former received perioperative administration of bivalirudin, while the latter received heparin.

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Cardiogenic shock.

Lancet

November 2024

Leipzig Heart Science, Leipzig, Germany; Department of Internal Medicine/Cardiology, Heart Center Leipzig at University of Leipzig, Leipzig, Germany. Electronic address:

Article Synopsis
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Article Synopsis
  • Mechanical circulatory support devices, especially the microaxial flow pump (mAFP), are being increasingly used to treat patients with cardiogenic shock resulting from acute myocardial infarction, with trials showing mixed results on their effectiveness.* -
  • A comparative analysis of mortality rates from the DanGer-SHOCK and ECLS-SHOCK trials revealed that the mAFP strategy correlated with a notable reduction in mortality at both 30 days and 6 months, suggesting it provides significant benefits over standard care.* -
  • The findings indicate that the DanGer unloading strategy, particularly when combined with percutaneous coronary intervention, enhances long-term survival in patients experiencing cardiogenic shock, although further research is necessary to validate these results across diverse patient groups
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Importance: Mechanical circulatory support with a microaxial flow pump (MAFP) has been shown to improve survival in ST-elevation myocardial infarction-induced cardiogenic shock (STEMI-CS). Understanding the impact on hemodynamic stability over time is crucial for optimizing patient treatment.

Objective: To determine if an MAFP reduces the need for pharmacological circulatory support without compromising hemodynamics compared with standard care in STEMI-CS.

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