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Langerhans Cell Histiocytosis Showed Intense Uptake of 68 Ga-FAPI. | LitMetric

AI Article Synopsis

  • - A 23-year-old man has been diagnosed with Langerhans cell histiocytosis (LCH), a rare disorder that affects the body's immune system.
  • - Imaging through 68 Ga-FAPI PET/CT revealed multiple lesions in his bones, indicating significant bone damage caused by LCH, along with some concerning areas near the heart and lungs.
  • - The findings suggest that 68 Ga-FAPI PET/CT could be a useful tool for assessing the extent and severity of LCH in patients.

Article Abstract

A 23-year-old man was recently diagnosed with Langerhans cell histiocytosis (LCH). 68 Ga-FAPI PET/CT showed multiple lesions with intense FAPI uptake in the axial and appendicular skeleton with lytic or mixed bone destruction, consistent with osseous lesions of LCH. FAPI-avid foci around the right atrium and inferior vena cava, as well as micronodules and thin-walled cysts in the lungs, were also noted, possibly also involvement of LCH. This case suggested that 68 Ga-FAPI PET/CT may have the potential to be applied in evaluation of LCH.

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Source
http://dx.doi.org/10.1097/RLU.0000000000004786DOI Listing

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