AI Article Synopsis

  • Headaches, especially migraines, are common in kids and teens, but effective treatments for them often lack FDA approval or supporting evidence.
  • Recent studies have examined both medication-based and non-medication-based treatments, showing promising safety and efficacy for options like onabotulinumtoxinA and CGRP antagonists.
  • A combined treatment approach is recommended for managing pediatric migraines, but more clinical studies are needed to evaluate these newer therapies.

Article Abstract

Purpose Of Review: Headaches are common in children and adolescents. Treatments for debilitating migraine are often not FDA approved or lack evidence of efficacy for children. This narrative review looks at the evidence for acute and preventative pharmacologic and non-pharmacologic treatment of pediatric migraine, as well as reviewing any recent or ongoing clinical trials.

Recent Findings: Studies have been published on pharmacological treatments for headache, as well as non-pharmacological treatments. Recent findings in pediatric migraine using onabotulinumtoxinA, calcitonin gene related peptide antagonists, interventional procedures, and devices are reviewed. Pharmacologic as well as non-pharmacologic approaches for the prevention and treatment of migraine show safety and efficacy data that is promising. These treatments should be incorporated in a multi-modal approach to the management of pediatric migraine. Continued studies, prospective and randomized, are needed to further assess these newer treatments for migraine in the pediatric setting.

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Source
http://dx.doi.org/10.1007/s11916-023-01157-8DOI Listing

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