We compared the serologic responses of 1 dose versus 2 doses of a variant vaccine (Moderna mRNA-1273 Beta/Omicron BA.1 bivalent vaccine) in adults. A 2-dose boosting regimen with a variant vaccine did not increase the magnitude or the durability of the serological responses compared to a single variant vaccine boost.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11032204PMC
http://dx.doi.org/10.1093/infdis/jiad323DOI Listing

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