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| http://dx.doi.org/10.5664/jcsm.10766 | DOI Listing |
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Drug-Induced Cauda Equina Syndrome in an 8-Year-Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report.
Clin Case Rep
January 2025
Pediatric Neurology Department, Pediatric Neurology Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8-year-old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplinary management are crucial.
View Article and Find Full Text PDFUnraveling the complexity: Case reports of drug-induced hemolytic anemia due to ceftriaxone.
Asian J Transfus Sci
August 2024
Department of Immunohematology and Transfusion Medicine, Santokba Durlabhji Memorial Hospital, Jaipur, Rajasthan, India.
Drug-induced hemolytic anemia (DIHA) is a rare but significant condition characterized by the premature destruction of red blood cells (RBCs) triggered by certain medications. Ceftriaxone, a commonly used antibiotic, has been linked to DIHA, presenting diagnostic challenges due to its diverse clinical manifestations. This study examines three cases of DIHA caused by ceftriaxone therapy at our center.
View Article and Find Full Text PDFA Rare Case of Erythromycin-Induced Rhabdomyolysis.
Cureus
December 2024
Internal Medicine, Staten Island University Hospital, Staten Island, USA.
Rhabdomyolysis (RML) arises from the breakdown of muscle tissue, leading to the release of intracellular components into the bloodstream and potentially causing multi-organ failure. Multiple drugs have been reported to cause RML. We present here a rare instance of erythromycin-triggered RML in a patient who was not on any other potential RML-inducing medications.
View Article and Find Full Text PDF[Drug-induced liver injury induced by nicotinamide: a case report].
Klin Padiatr
January 2025
Vergiftungs-Informations-Zentrale Freiburg, Universitätsklinikum Freiburg Zentrum für Kinder- und Jugendmedizin, Freiburg, Germany.
Artificial liver support systems bridge severe immune-mediated hepatotoxicity to clinical recovery.
Immunopharmacol Immunotoxicol
January 2025
Department of Medical Oncology, The First Affiliated Hospital of Zhejiang University School of Medicine, 310003 Hangzhou, China.
Background: The incidence of hepatic immune-related adverse events has increased with the wide use of immune checkpoint inhibitors, some immune-mediated hepatotoxicity cases are severe and lack of clinical recommendations.
Objective: This study aimed to evaluate the efficacy of artificial liver support systems (ALSS) in the treatment of immune-mediated hepatotoxicity.
Methods: This retrospective case series included six patients with grade 4 hepatotoxicity with high bilirubin induced by immune checkpoint inhibitors treated between January 1, 2019, to December 31, 2021.
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