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Effects of pregnancy-induced hypertension on early-onset neonatal thrombocytopenia.
BMC Pregnancy Childbirth
January 2025
Department of Neonatology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Enze Hospital, Taizhou Enze Medical Center (Group), 1 East Tongyang Road, Tongyu Street, Luqiao, 318050, Zhejiang, China.
Background: Gestational hypertension and preeclampsia are potentially linked to similar pathophysiological processes. Maternal preeclampsia increases the occurrence of early-onset neonatal thrombocytopenia. We hypothesized that maternal gestational hypertension may impact the incident early-onset neonatal thrombocytopenia.
View Article and Find Full Text PDFThe Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection.
J Fungi (Basel)
December 2024
Laboratory of Haematology and Blood Bank Unit, "Attikon" Hospital, National and Kapodistrian University of Athens Medical School, 12462 Athens, Greece.
Background: Systemic infection (SCI) is the third most common cause of late-onset sepsis in Neonatal Intensive Care Units (NICU). While platelet involvement in fungal infections has been extensively studied, evaluation of the hemostatic mechanism in Candida infections, especially in neonates, has not been widely investigated. The aim of the current study was to evaluate the hemostatic profile of neonates with SCI through rotational thromboelastometry (ROTEM), a laboratory method that assesses the viscoelastic properties of blood.
View Article and Find Full Text PDFA nomogram for predicting neonatal acute respiratory distress syndrome in patients with neonatal pneumonia after 34 weeks of gestation.
Front Pediatr
January 2025
Department of Pediatrics, Dandong Central Hospital, China Medical University, Dandong, China.
Objective: To establish a prediction nomogram for early prediction of neonatal acute respiratory distress syndrome (NARDS).
Methods: This is a retrospective cross-sectional study conducted between January 2021 and December 2023. Clinical characteristics and laboratory results of cases with neonatal pneumonia were compared in terms of presence of NARDS diagnosis based on the Montreux Definition.
Neutrophil-to-Lymphocyte Ratio and Other Complete Blood Count Parameters in the Diagnosis of Serious Bacterial Infections in Febrile Infants Under Three Months.
Cureus
December 2024
Pediatrics, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Athens, GRC.
Background: The incidence of serious bacterial infections (SBI) in febrile infants under three months is high. Complete blood count parameters, an easily accessible and low-cost test, may have diagnostic potential for SBI.
Objectives: This study evaluated the efficacy of absolute neutrophil count (ANC), neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), platelet-to-mean platelet volume ratio (PLT/MPV), red cell distribution width (RDW), and C-reactive protein (CRP) in distinguishing febrile infants under three months with SBI.
Pharmacological depletion of pericytes induces diabetic retinopathy-like abnormal blood vessels in neonatal rat retina.
Exp Eye Res
January 2025
Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane Minato-ku, Tokyo, 108-8641, Japan. Electronic address:
Diabetic retinopathy is a major ocular complication associated with diabetes mellitus. Pericyte loss is a hallmark of diabetic retinopathy. The platelet-derived growth factor (PDGF)-B-PDGF receptor-β (PDGFRβ) signaling pathway plays an important role in the proliferation and migration of pericytes.
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