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Cerebral Venous Sinus Thrombosis as a Unique Initial Presentation of Thyroid Storm.
Neurologist
January 2025
Public Health, Khamis Mushayt General Hospital, Khamis Mushait, Saudi Arabia.
Introduction: Thyrotoxicosis is associated with a hypercoagulable state, increasing the risk of thrombotic events like CVST. Literature review reveals thyroid hormone's role in promoting prothrombotic abnormalities, impacting coagulation factors and platelet function.
Case Report: This study explores the rare occurrence of thyroid storm complicated by deep cerebral venous sinus thrombosis (CVST) in a young male with no prior history of thyroid disease.
Pediatric Graves' disease in Argentina: analyzing treatment strategies and outcomes.
J Pediatr Endocrinol Metab
December 2024
CONICET-FEI-División de Endocrinología, Centro de Investigaciones Endocrinológicas"Dr. César Bergadá" (CEDIE), Hospital de Niños Ricardo Gutiérrez, BuenosAires, Argentina.
Objectives: Graves' disease is the leading cause of hyperthyroidism in children. Only a small percentage of pediatric patients achieve remission with anti-thyroid drug treatment (ATD), and both definitive therapies (thyroidectomy, or radioiodine thyroid ablation) cause lifelong hypothyroidism. Our objective was to evaluate the outcome of patients with pediatric Graves' disease (PGD), treated at a single tertiary center, focusing on response to medical treatment, remission rate, adverse reactions (AR), definitive treatment (DT), and potential predictive factors for remission.
View Article and Find Full Text PDFObesity and postpartum hospital use among individuals without additional medical comorbidities.
Obesity (Silver Spring)
January 2025
Department of Obstetrics & Gynecology, Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Objective: The objective of this study was to examine whether obesity without preexisting or gestational comorbidities is associated with postpartum hospital use (PHU).
Methods: We studied 2016 to 2018 birth certificate and discharge data on 178,729 New York City births without International Classification of Diseases, Tenth Revision (ICD-10) codes at delivery for diabetes; hypertension; placental disease; anemia; thyrotoxicosis; bariatric surgery; and pulmonary, cardiac, renal, bleeding, autoimmune, digestive, neuromuscular, mental, or substance-use disorders. We defined PHU as ≥1 readmission or emergency department visit within 30 days of delivery discharge.
Unusual Management of a Rare Case of Methimazole-Resistant Graves Disease.
JCEM Case Rep
January 2025
Baylor University Medical Center, Dallas, TX 75246, USA.
Article Synopsis
- Graves disease (GD) is the main cause of hyperthyroidism but often shows different symptoms like tachycardia and weight loss instead of the typical signs.
- Treatment options include antithyroid drugs (ATDs), radioactive iodine (RAI), and surgery, each with notable side effects and potential complications such as ATD resistance.
- A complex case study of a 58-year-old woman with MMI-resistant GD illustrates the difficulties in treatment, leading to successful management with RAI therapy after unsuccessful attempts with high doses of MMI.
Clinical and genetic characteristics of patients with monocarboxylate transporter-8 deficiency: a multicentre retrospective study.
Eur J Pediatr
December 2024
Department of Pediatric Endocrinology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Unlabelled: Allan-Herndon-Dudley syndrome is a neurodevelopmental disorder characterized by motor and intellectual disabilities. Despite its rarity, there has been a rise in interest due to ongoing research and emerging therapy suggestions. In this multicenter, retrospective, cross-sectional study, the genetic characteristics and clinical data of twenty-one cases of genetically confirmed MCT8 deficiency were evaluated.
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