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| http://dx.doi.org/10.1001/jamanetworkopen.2023.28117 | DOI Listing |
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Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or , but the keys to some important biomedical questions may simply not be found in these.
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View Article and Find Full Text PDFUnlabelled: Transparent and accurate reporting in early phase dose-finding (EPDF) clinical trials is crucial for informing subsequent larger trials. The SPIRIT statement, designed for trial protocol content, does not adequately cover the distinctive features of EPDF trials. Recent findings indicate that the protocol contents in past EPDF trials frequently lacked completeness and clarity.
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View Article and Find Full Text PDFHigh-speed silicon traveling-wave Mach-Zehnder modulators (MZMs) are key components to support optical fiber communication. However, one major challenge with all-silicon MZMs is to achieve efficient high-speed electro-optic (EO) modulation. The reported 3 dB bandwidth of silicon MZMs are generally below 70 GHz, with half-wave voltage ( ) around 5 V or larger, which can not support future 200 Gbaud data transmission.
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