New kids on the block: and gene.

and proto-oncogens are involved in a wide variety of tumourigenic processes. and gene rearrangements are observed in epithelioid haemangioma, pseudomyogenic haemangioendothelioma, osteoid osteoma/osteoblastoma/cementoblastoma and proliferative myositis/fasciitis. In this review, we provide an overview of and including their functions and the differences between lesions with known gene rearrangements. Additionally, we discuss the use of / immunohistochemistry as a diagnostic tool for these lesions.