In indoor environments with limited ventilation, recirculating portable air filtration (PAF) units may reduce COVID-19 infection risk via not only the direct aerosol route (i.e., inhalation) but also via an indirect aerosol route (i.e., contact with the surface where aerosol particles deposited). We systematically investigated the impact of PAF units in a mock classroom, as a supplement to background ventilation, on localized and whole-room surface deposition and particle concentration. Fluorescently tagged particles with a volumetric mean diameter near 2 μm were continuously introduced into the classroom environment via a breathing simulator with a prescribed inhalation-exhalation waveform. Deposition velocities were inferred on >50 horizontal and vertical surfaces throughout the classroom, while aerosol concentrations were spatially monitored via optical particle spectrometry. Results revealed a particle decay rate consistent with expectations based upon the reported clean air delivery rates of the PAF units. Additionally, the PAF units reduced peak concentrations by a factor of around 2.5 compared to the highest concentrations observed and led to a statistically significant reduction in deposition velocities for horizontal surfaces >2.5 m from the aerosol source. Our results not only confirm that PAF units can reduce particle concentrations but also demonstrate that they may lead to reduced particle deposition throughout an indoor environment when properly positioned with respect to the location of the particle source(s) within the room (e.g., where the largest group of students sit) and the predominant air distribution profile of the room.
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http://dx.doi.org/10.1021/acsestengg.1c00321 | DOI Listing |
Crit Care
January 2025
HCor Research Institute, Hospital do Coração, Rua Desembargador Eliseu Guilherme 200, 8th Floor, São Paulo, SP, 04004-030, Brazil.
Background: Limited data is available to evaluate the burden of device associated healthcare infections (HAI) [central line associated bloodstream infection (CLABSI), catheter associated urinary tract infection (CAUTI), and ventilator associated pneumonia (VAP)] in low and-middle-income countries. Our aim is to investigate the population attributable mortality fraction and the absolute mortality difference of HAI in a broad population of critically ill patients from Brazil.
Methods: Multicenter cohort study from September 2019 to December 2023 with prospective individual patient data collection.
J Phys Chem Lett
November 2024
Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Previous studies have reported that [PdAu(PA)] (PA = 3,5-(CF)CHC≡C) with an icosahedral superatomic PdAu(8e) core underwent collision-induced sequential reductive elimination (CISRE) of 1,3-diyne (PA) ( 2020, 124, 19119). The most likely scenario after the CISRE of (PA) is the growth of the PdAu(8e) core via the fusion of the Au(0) atoms produced from the Au(PA) units on the core surface. Contrary to expectation, anion photoelectron spectroscopy and theoretical calculations regarding the CISRE products [PdAu(PA)] ( = 1-6) revealed that the electronically closed PdAu(8e) core does not grow to a single superatom with (8 + 2)e but assembles with Au(2e) units.
View Article and Find Full Text PDFNanoscale
June 2024
Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education, College of Chemistry, Northeast Normal University, Changchun 130024, P. R. China.
The development of efficient and recyclable photocatalysts for organic synthesis is of great interest. This study presents the synthesis of triphenylamine-based porous aromatic frameworks (TPA-PAFs) in an alternating donor-acceptor (D-A) manner. The light absorption range and the optical band gaps of TPA-PAFs are effectively tuned by changing the electron acceptor units, which further determine their photocatalytic properties.
View Article and Find Full Text PDFChemistry
July 2024
Key Laboratory of Polyoxometalate and Reticular Material Chemistr y of Ministry of Education, Faculty of Chemistry, Northeast Normal University, Changchun, 130024, China.
Porous aromatic frameworks (PAFs) are highly promising functional porous solids known for their feasible amenability and extraordinary stability. When the framework was modified by ionic functional groups, these ionic PAFs (iPAFs) exhibited charged channels for adsorption, separation, and catalysis. However, the surface areas of ionic porous frameworks are usually lower than that of neutral frameworks, and their synthesis is limited by specific strategies and complex modification processes.
View Article and Find Full Text PDFBackground: Asthma remains a common cause of hospital admissions across the life course. We estimated the contribution of key risk factors to asthma-related hospital and intensive care unit (ICU) admissions in children, adolescents and adults.
Methods: This was a UK-based cohort study using linked primary care (Clinical Practice Research Datalink Aurum) and secondary care (Hospital Episode Statistics Admitted Patient Care) data.
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