Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10863-023-09981-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Optimized automated radiosynthesis of F-JNJ64413739 for purinergic ion channel receptor 7 (P2X7R) imaging in osteoporotic model rats.
Front Pharmacol
December 2024
Department of Nuclear Medicine, The First Affiliated Hospital, Jinan University, Guangzhou, China.
Objective: To optimize the automated radiosynthesis of the purinergic ion channel receptor 7 (P2X7R) imaging agent F-JNJ64413739 and evaluate its potential for brain imaging in osteoporotic model rats.
Methods: A more electron-deficient nitropyridine was employed as the labeling precursor to facilitate the F-labeling. The radiosynthesis was conducted on an AllinOne synthesis module, and followed by purification via high-performance liquid chromatography (HPLC).
Correction to: Role and recent progress of P2Y12 receptor in cancer development.
Purinergic Signal
October 2024
Department of General Surgery, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, Jiangxi, 332007, People's Republic of China.
Platelet inhibitor withdrawal and outcomes after coronary artery surgery: an individual patient data meta-analysis.
Eur J Cardiothorac Surg
July 2024
Division of Cardiology, University Heart Center Graz, Medical University of Graz, Graz, Austria.
Article Synopsis
- The study aimed to investigate the impact of following guideline-recommended withdrawal periods of P2Y12 receptor inhibitors before on-pump coronary artery bypass grafting (CABG) on bleeding and ischemic events, noting a lack of randomized controlled trials in this area.
- Researchers analyzed data from 7 observational studies involving 4,837 patients who underwent CABG, measuring severe bleeding (BARC-4) and postoperative ischemic events.
- Results indicated that adhering to suggested withdrawal times significantly reduced the risk of severe bleeding for clopidogrel users while showing a similar trend for ticagrelor, with no significant change in 30-day mortality but a decrease in ischemic events for clopidogrel users.
Protection from environmental enteric dysfunction and growth improvement in malnourished newborns by amplification of secretory IgA.
Cell Rep Med
July 2024
Institute for Research in Biomedicine, Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland. Electronic address:
Environmental enteric dysfunction (EED) is a condition associated with malnutrition that can progress to malabsorption and villous atrophy. Severe EED results in linear growth stunting, slowed neurocognitive development, and unresponsiveness to oral vaccines. Prenatal exposure to malnutrition and breast feeding by malnourished mothers replicates EED.
View Article and Find Full Text PDFCorrection to: Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist.
Purinergic Signal
December 2024
PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, 53121, Bonn, Germany.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!