AI Article Synopsis
- Acute myeloid leukemia (AML) has varied symptoms and a generally poor outlook, primarily treated with traditional chemotherapy.
- Recent advancements in next-generation sequencing technology are leading to more precise targeted therapies focused on molecular biology and patient characteristics.
- New small-molecule inhibitors and immune-targeted drugs offer promising alternatives for patients who can't handle standard chemotherapy, boasting better efficacy and fewer side effects.
Article Abstract
Acute myeloid leukemia (AML) has highly heterogeneous clinical manifestations and poor prognosis, and traditional chemotherapy is the main treatment. In recent years, with the in-depth development of next-generation sequencing technology, the treatment of AML is gradually exploring the precise targeted therapy in the direction of molecular biology and immunophenotype. The advent of various small-molecule inhibitors and immune-targeted drugs has brought hope to patients who cannot tolerate intensive chemotherapy or with relapsed/refractory AML. Compared with traditional chemotherapy, targeted therapy has the advantages of significant curative effect and fewer adverse effects. This article reviews the latest research progress of targeted drug therapy for AML.
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| http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2023.04.051 | DOI Listing |
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