Dietary intervention is an essential factor in managing a multitude of chronic health conditions such as cardiovascular and chronic kidney disease. In recent decades, there has been a host of research suggesting the potential benefit of plant-based diets in mitigating the health outcomes of these conditions. Plant-based diets are rich in vegetables and fruits, while limiting processed food and animal protein sources. The underlying physiological mechanism involves the interaction of several macronutrients and micronutrients such as plant protein, carbohydrates, and dietary potassium. Specifically, plant-based foods rich in potassium provide cardiorenal protective effects to include urinary alkalization and increased sodium excretion. These diets induce adaptive physiologic responses that improve kidney and cardiovascular hemodynamics and improve overall metabolic health. A shift toward consuming plant-based diets even in subjects with cardiorenal decrements may reduce their morbidity and mortality. Nonetheless, randomized controlled trials are needed to confirm the clinical benefits of plant-based diets.
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http://dx.doi.org/10.1016/j.semnephrol.2023.151406 | DOI Listing |
Br J Nutr
January 2025
Division of Nephrology, Department of Internal Medicine, Koc University School of Medicine, Istanbul, Turkey.
This interventional single-center prospective open-label study aims to evaluate the effects of a vegan diet, compared to a vegetarian and omnivorous diet, on metabolic parameters, insulin sensitivity, and liver and kidney steatosis in healthy adults. The study included 53 omnivorous participants aged 18-40 years, body-mass index 18-30 kg/m2, without any chronic disease, chronic medication use, active smoking, or significant alcohol consumption. All participants were omnivorous at baseline and selected to continue an omnivorous diet or transition to a vegetarian or vegan diet, with follow-up over six months.
View Article and Find Full Text PDFAppetite
January 2025
Department of Family Relations and Applied Nutrition, University of Guelph, Guelph, Canada. Electronic address:
The primary objective of this research was to evaluate the feasibility and acceptability of "Supper Heroes", a superhero-themed mobile health (mHealth) intervention designed to reduce food waste and increase plant-based protein food intake among families with children aged 9-14 in Ontario, Canada. A single arm, pre-post mixed methods design was used to evaluate the intervention. The 4-month mHealth intervention included 7 online modules with infographics, videos, and activities to help families reduce their food waste and eat more plant-based protein foods.
View Article and Find Full Text PDFNutr Rev
December 2024
Department of Nutrition and Dietetics, Kent University, 34406 İstanbul, Türkiye.
Context: Rheumatoid arthritis (RA) is an autoimmune disease that leads to chronic inflammation and joint damage. Various plant-based diets are thought to have effects on RA symptoms and disease activity.
Objective: Relevant literature on the effect of different types of plant-based diets on RA was reviewed.
Alzheimers Dement
December 2024
Wake Forest Alzheimer's Disease Research Center, Winston-Salem, NC, USA.
Background: Diet composition is associated with neurodegenerative disease risk including Alzheimer's Disease (AD). The adverse effects of Western-style diets may be moderated, in part, by systemic as well as central inflammation, whereas the neuroprotective effects of Mediterranean diets may work through mechanisms that promote anti-inflammatory phenotypes. Systemic inflammation also may induce insulin resistance, another risk factor for AD.
View Article and Find Full Text PDFBackground: Interest and consumption of plant-based diets (PBD) in the 21 century continued to increase, particularly in western societies, with the perception that PBDs are associated with beneficial health outcomes and a reduced environmental footprint. Evidence suggests that PBDs may be protective against neurodegenerative diseases, such as Alzheimer's disease (AD). Health effects of PBDs such as reduction of inflammation, shift in gut microbiota composition, reduced risk of type 2 diabetes and cardiovascular disease are all believed to attribute to reduced AD risk.
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