Osteogenesis surrounding dental implants is initiated by a series of early physiological events, including the inflammatory response. However, the persistence of an anti-infection surface often results in compromised histocompatibility and osseointegration. Here, we presented a programmed surface containing both silver nanoparticles (AgNPs) and silver ions (Ag) with a heterogeneous structure and time-dependent functionalities. The AgNPs were located at the surface of the heparin-chitosan polyelectrolyte coating (PEM), whereas Ag was distributed at both the surface and inside of the coating under optimized conditions (pH=4). The optimized coating (Ag-4) exhibited potent bactericidal activity at the early stage (12 and 24 h after inoculation) and a sustained antibacterial efficacy in the subsequent stage (one or two weeks), as it gradually depleted. Furthermore, compared to coatings with sustained high silver concentrations in bacteria-cell coculture experiments, the degradable Ag-4 coating demonstrated improved cytocompatibility, better cell viability, and morphology over time. At a later stage (within one month), the in vivo test revealed that Ag-4-coated titanium had superior histocompatibility and osteogenesis outcomes compared to bare titanium in a bacteria-exposed environment. The programmed surface of dental implants presented in this study offers innovative ideas for sequential antibacterial effects and osseointegration.
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http://dx.doi.org/10.1016/j.colsurfb.2023.113477 | DOI Listing |
Sensors (Basel)
December 2024
Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, School of Materials Science & Engineering, Hubei University, Wuhan 430062, China.
The MEMS gas sensor is one of the most promising gas sensors nowadays due to its advantage of small size, low power consumption, and easy integration. It has been widely applied in energy components, portable devices, smart living, etc. The performance of the gas sensor is largely determined by the sensing materials, as well as the fabrication methods.
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December 2024
Institute of Communications Engineering, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
A core dielectric cylindrical rod wrapped in a dielectric circular pipe whose outer surface is enclosed by a helical conducting strip grating that is skewed along the axial direction is herein analyzed using the asymptotic strip boundary conditions along with classical vector potential analysis. Targeted for use as a cylindrical holographic antenna, the resultant field solutions facilitate the aperture integration of the equivalent cylindrical surface currents to obtain the radiated far fields. As each rod section of a certain skew angle exhibits a distinct modal attribute; this topology allows for the distribution of the cylindrical surface impedance via the effective refractive index to be modulated, as in gradient-index (GRIN) materials.
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December 2024
School of Mechanical Engineering and Automation, Foshan University, Foshan 528225, China.
Inspection robots, which improve hazard identification and enhance safety management, play a vital role in the examination of high-risk environments in many fields, such as power distribution, petrochemical, and new energy battery factories. Currently, the position precision of the robots is a major barrier to their broad application. Exact kinematic model and control system of the robots is required to improve their location accuracy during movement on the unstructured surfaces.
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December 2024
Department of Chemistry and Biochemistry, Institute of Fluorescence, University of Maryland, Baltimore County, 701 E Pratt St, Baltimore, MD 21202, USA.
We report on the detection and quantification of aqueous DNA by a fluorophore-induced plasmonic current (FIPC) sensing method. FIPC is a mechanism described by our group in the literature where a fluorophore in close proximity to a plasmonically active metal nanoparticle film (MNF) is able to couple with it, when in an excited state. This coupling produces enhanced fluorescent intensity from the fluorophore-MNF complex, and if conditions are met, a current is generated in the film that is intrinsically linked to the properties of the fluorophore in the complex.
View Article and Find Full Text PDFPharmaceutics
December 2024
Basic Research Key Laboratory of General Surgery for Digital Medicine, Affiliated Hospital of Hebei University, Baoding 071000, China.
: Postoperative abdominal adhesion is a prevalent complication following abdominal surgery, with the incidence of adhesion reaching up to 90%, which may precipitate a range of adverse outcomes. Although fibrous membranes loaded with various anti-inflammatory or other drugs have been proposed for anti-adhesion, most of them suffer from drug-induced adverse effects. : In this study, a lecithin-based electrospun polylactic acid (PLA) nanofibrous membrane (L/P-NM) was developed for the prevention of postoperative abdominal adhesion, utilizing the hydration lubrication theory.
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