AI Article Synopsis
- - The study investigates how functional amyloid fibers impact melanogenesis and their connection to the spin properties of melanin, which haven't been thoroughly studied before.
- - Researchers found that introducing an amyloid scaffold enhances the spin density in synthetic melanin while also improving its water dispersibility and UV protection abilities.
- - This research sheds light on the vital role of functional amyloid in melanin production and suggests why natural melanin outperforms synthetic versions in terms of spin-related characteristics.
Article Abstract
Functional amyloid fibers are crucial in melanogenesis, but their roles are incompletely understood. In particular, their relationship with intrinsic spin characters of melanin remains unexplored. Here, we show that adding an amyloid scaffold greatly augments the spin density in synthetic melanin. It also brings about concurrent alterations in water dispersibility, bandgaps, and radical scavenging properties of the synthetic melanin, which facilitates its applications in solar water remediation and protection of human keratinocytes from UV irradiation. This work provides implications in the unrevealed role of functional amyloid in melanogenesis and in the origin of the superiority of natural melanin toward its synthetic variants in terms of the spin-related properties.
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| http://dx.doi.org/10.1021/acsami.3c07909 | DOI Listing |
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