Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41593-023-01412-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
External globus pallidus input to the dorsal striatum regulates habitual seeking behavior in male mice.
Nat Commun
July 2023
Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.
The external globus pallidus (GPe) coordinates action-selection through GABAergic projections throughout the basal ganglia. GPe arkypallidal (arky) neurons project exclusively to the dorsal striatum, which regulates goal-directed and habitual seeking. However, the role of GPe arky neurons in reward-seeking remains unknown.
View Article and Find Full Text PDFArkypallidal Cells Send a Stop Signal to Striatum.
Neuron
January 2016
Universite de Bordeaux, Institut des Maladies Neurodegeneratives, 33076 Bordeaux, France
The suppression of inappropriate actions is critical for flexible behavior. Cortical-basal ganglia networks provide key gating mechanisms for action suppression, yet the specific roles of neuronal subpopulations are poorly understood. Here, we examine Arkypallidal (‘‘Arky’’) and Prototypical (‘‘Proto’’) globus pallidus neurons during a Stop task, which requires abrupt cancellation of an imminent action.
View Article and Find Full Text PDFGenetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.
Diabetes Care
February 2012
Diabetes Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.
Objective: We tested genetic associations with weight loss and weight regain in the Diabetes Prevention Program, a randomized controlled trial of weight loss-inducing interventions (lifestyle and metformin) versus placebo.
Research Design And Methods: Sixteen obesity-predisposing single nucleotide polymorphisms (SNPs) were tested for association with short-term (baseline to 6 months) and long-term (baseline to 2 years) weight loss and weight regain (6 months to study end).
Results: Irrespective of treatment, the Ala12 allele at PPARG associated with short- and long-term weight loss (-0.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!