General Multiscenario Ultrasound Image Tumor Diagnosis Method Based on Unsupervised Domain Adaptation.

Objective: The utilization of computer-aided diagnosis (CAD) in breast ultrasound image classification has been limited by small sample sizes and domain shift. Current ultrasound classification methods perform inadequately when exposed to cross-domain scenarios, as they struggle with data sets from unobserved domains. In the medical field, there are situations in which all images must share the same networks as they capture the same symptom of the same participant, implying that they share identical structural content. Nevertheless, most domain adaptation methods are not suitable for medical images as they overlook the common features among the images.

Methods: To overcome these challenges, we propose a novel diverse-domain 2-D feature selection network (FSN), which uses the similarities among medical images and extracts features with a reconstruction network with shared weights. Additionally, it penalizes the feature domain distance through two adversarial learning modules that align the feature space and select common features. Our experiments illustrate that the proposed method is robust and can be applied to ultrasound images of various diseases.

Results: Compared with the latest domain adaptive methods, 2-D FSN markedly enhances the accuracy of classification of breast, thyroid and endoscopic ultrasound images, achieving accuracies of 82.4%, 96.4% and 89.7%, respectively. Furthermore, the model was evaluated on an unsupervised domain adaptation task using ultrasound images from multiple sources and achieved an average accuracy of 77.3% across widely varying domains.

Conclusion: In general, 2-D FSN improves the classification ability of the model on multidomain ultrasound data sets through the learning of common features and the combination of multimodule intelligence. The algorithm has good clinical guidance value.