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Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China.
PLoS Negl Trop Dis
January 2025
Department of Neonatology, National Children's Medical Center/Children's Hospital of Fudan University, National Health Commission (NHC) Key Laboratory of Neonatal Diseases, Shanghai, China.
Background: Despite its association with high mortality rates and negative fetal outcomes, large-scale epidemiological studies on scrub typhus (ST) during pregnancy remain scarce.
Methods: We conducted a retrospective, multicenter study by collecting 260 pregnant women with ST in China across a 10-year time period to evaluate how clinical characteristics changed over this time and identify risk factors for poor fetal outcome.
Results: In total, 78.
Changes in seasonality and sex ratio of scrub typhus: a case study of South Korea from 2003 to 2019 based on wavelet transform analysis.
BMC Infect Dis
September 2024
Department of Preventive Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
Article Synopsis
- Scrub typhus (ST) is a prevalent vector-borne disease in South Korea that shows changes in seasonality and sex distribution, highlighting the importance of understanding these patterns for effective health interventions.
- An analysis of ST cases from 2003 to 2019 revealed a significant increase in incidence until 2012, followed by a substantial decrease, with a dual seasonal pattern showing more cases in autumn and fewer in spring.
- The male-to-female ratio of ST cases increased slightly over the years, but there were notable variations across different age groups, indicating diverse demographic impacts that warrant further monitoring and research.
Bedside bilateral sequential intravitreal anti-VEGF injections for retinopathy of prematurity.
Indian J Ophthalmol
January 2025
Vitreoretinal Services, Grewal Eye Institute, Chandigarh, India.
Purpose: To evaluate the outcome and ocular adverse events of bedside bilateral sequential intravitreal anti-vascular endothelial growth factor injections for retinopathy of prematurity (ROP) (BBSIR).
Methods: This retrospective interventional study included infants who received BBSIR with a follow-up of at least 1 month. Clinical history, intravitreal injection details, indications, intraoperative and postoperative ocular adverse events, and outcomes were analyzed.
Foetal outcome of Leptospira and Rickettsial infections during pregnancy: a systematic review.
Trans R Soc Trop Med Hyg
December 2024
Department of Pharmacology, All India Institute of Medical Sciences, Kalyani, West Bengal, India741245.
Article Synopsis
- Leptospirosis and rickettsial infections, including scrub typhus, are bacterial diseases that can severely affect pregnant women and their babies, leading to overlapping symptoms.* -
- A study analyzed 54 research papers to evaluate the effects of these infections on fetal outcomes, revealing significant cases of fetal loss and maternal deaths associated with scrub typhus and leptospirosis.* -
- The findings highlight the need for more research to understand these infections better and develop strategies to protect pregnant women and improve outcomes for their infants.*
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