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Tenofovir-associated Fanconi Syndrome in liver transplant recipients with hepatitis B: A retrospective case series.
Am J Transplant
December 2024
Division of Gastroenterology, Hepatology, and Nutrition, University of Minnesota, Minneapolis, MN. Electronic address:
Tenofovir-associated Fanconi Syndrome (TAFS) is a proximal renal tubule disorder rarely reported in patients after liver transplantation (LT) for hepatitis B (HBV). In a retrospective review of 79 HBV-LT recipients, 8/66 (12.1%) on tenofovir post-LT developed TAFS.
View Article and Find Full Text PDFClinicopathological characteristics of light chain proximal tubulopathy: a multicentre case series.
J Clin Pathol
December 2024
National Clinical Research Center for Kidney Diseases, Jinling Hospital, Nanjing Medical University, Nanjing, China
Aims: Light chain proximal tubulopathy (LCPT) is a rare complication of paraprotein-related diseases. We report a case series to present the clinicopathological characteristics and outcomes of LCPT.
Methods: A multicentre retrospective case series of 47 patients with LCPT, consisting of 36 crystalline, three non-crystalline, and eight mixed LCPTs, was studied between January 2007 and December 2023.
Fanconi syndrome following administration of oral supplements containing red yeast rice: several months follow-up of three cases.
CEN Case Rep
December 2024
Department of Nephrology, Faculty of Medicine, Juntendo University, 3-1-3 Hongou, Bunkyo-ku, Tokyo, 133-8431, Japan.
Article Synopsis
- The long-term effects and treatment of acute kidney injury (AKI) from the red yeast rice supplement Benikoji CholesteHelp are not fully understood, but three cases of renal dysfunction improved after stopping the supplement.
- In the first case, a 59-year-old woman developed severe renal impairment and Fanconi syndrome after 7 months of use, but her kidney function gradually improved over three months post-discontinuation, though not back to baseline levels.
- The other two cases involved men aged 48 and 47 who experienced mild renal dysfunction after taking the supplement for 2 and 4 months, respectively, both of which showed significant improvement after stopping the supplement, indicating that discontinuation may reverse renal impairment in these scenarios.
Investigation of glucosuria in children.
Minerva Pediatr (Torino)
December 2024
Department of Pediatrics, Second Faculty of Medicine, Motol University Hospital, Charles University, Prague, Czech Republic.
Article Synopsis
- Previous recommendations on diagnosing familial renal glucosuria lacked a comprehensive understanding of glucosuria's differential diagnosis.
- This review aims to summarize the various causes of glucosuria and propose an evidence-based diagnostic approach for children affected by it.
- The findings indicate that several factors, including genetic and acquired conditions, can impact glucose reabsorption in the kidneys, necessitating the exclusion of diabetes mellitus and other hyperglycemia-related conditions before making a diagnosis.
Fanconi syndrome with acute proximal tubular injury induced by a dietary supplement containing beni-koji: a case series report.
BMC Nephrol
December 2024
Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Background: Fanconi syndrome is a disorder of the proximal tubule that leads to malabsorption of various electrolytes and substances and is a common consequence of drug-induced nephrotoxicity. However, cases of dietary supplement-induced Fanconi syndrome are rare, and detailed reports on the evaluation of renal histology in patients with this syndrome are lacking.
Case Presentation: We present two cases of dietary supplement-induced Fanconi syndrome that was confirmed by kidney biopsy.
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