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Country-specific key lifestyle factors and health outcomes for resource allocation in the general population: a network analysis across 29 countries.
J Glob Health
January 2025
Medical-surgical Nursing Department, Faculty of Nursing, Cairo University, Cairo, Egypt.
Background: We aimed to identify the central lifestyle, the most impactful among lifestyle factor clusters; the central health outcome, the most impactful among health outcome clusters; and the bridge lifestyle, the most strongly connected to health outcome clusters, across 29 countries to optimise resource allocation for local holistic health improvements.
Methods: From July 2020 to August 2021, we surveyed 16 461 adults across 29 countries who self-reported changes in 18 lifestyle factors and 13 health outcomes due to the pandemic. Three networks were generated by network analysis for each country: lifestyle, health outcome, and bridge networks.
Impact of a very low-calorie ketogenic diet on metabolic and microbiota outcomes in post-bariatric patients and bariatric-Naïve individuals: A comparative pilot study.
Diabetes Obes Metab
January 2025
Section of Medical Pathophysiology, Food Science and Endocrinology, Department of Experimental Medicine, Sapienza University, Rome, Italy.
Aims: To date, bariatric surgery (BS) is the most effective long-term treatment for obesity, but weight regain (WR) is common. The very low-calorie ketogenic diet (VLCKD) is effective for weight loss and may influence gut microbiota (GM) composition, but it has been scarcely evaluated in post-bariatric patients. This study compared the efficacy and safety of a VLCKD in patients with WR post-bariatric surgery (BS+) and in bariatric surgery-naïve patients (BS-).
View Article and Find Full Text PDFInvestigating the presence of surgical learning in the Timing of Primary Surgery for cleft palate randomised trial.
Clin Trials
January 2025
Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, UK.
Background/aims: When conducting a randomised controlled trial in surgery, it is important to consider surgical learning, where surgeons' familiarity with one, or both, of the interventions increases during the trial. If present, learning may compromise trial validity. We demonstrate a statistical investigation into surgical learning within a trial of cleft palate repair.
View Article and Find Full Text PDFNGR1 reduces neuronal apoptosis through regulation of ITGA11 following subarachnoid hemorrhage.
Mol Med Rep
March 2025
State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, SAR 999078, P.R. China.
Subarachnoid hemorrhage (SAH), a prevalent cerebrovascular condition associated with a high mortality rate, frequently results in neuronal apoptosis and an unfavorable prognosis. The adjunctive use of traditional Chinese medicine (TCM) with surgical interventions exerts a therapeutic impact on SAH, potentially by facilitating apoptosis. However, the mechanism by which TCM mediates apoptosis following SAH remains unclear.
View Article and Find Full Text PDFManagement of Impacted Primary Molar Obstructing Permanent Tooth Eruption in a Pediatric Patient: A Case Report.
Cureus
December 2024
Pediatric and Preventive Dentistry, Dr. Hedgewar Smruti Rugna Sewa Mandal's Dental College and Hospital, Hingoli, IND.
Tooth impaction and eruption failure present common challenges in pediatric dentistry. We report a case of a 10-year-old boy of Indian origin presenting with a missing left mandibular primary second molar and impacted first permanent molar. Radiographic examination revealed an ankylosed primary molar obstructing the path of an unerupted premolar.
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