AI Article Synopsis

  • Scrub typhus is a significant rickettsial infection prevalent in low- and middle-income countries, and this study aimed to evaluate the hospitalization costs associated with it over a six-year period.
  • A retrospective analysis of 198 patients revealed that the average hospitalization cost was ₹ 37,026 ($490), with ICU admissions costing significantly more at ₹ 128,046 ($1695) compared to standard wards at ₹ 33,232 ($440).
  • Key factors increasing hospitalization costs included acute respiratory distress syndrome (ARDS), higher SOFA scores, and longer hospital stays, highlighting the financial burden of scrub typhus treatment.

Article Abstract

Background & Objectives: Scrub typhus is a rickettsial infection seen along the Asian-Pacific rim and imposes a considerable burden on affected people in low- and middle-income countries. The present study was aimed to determine the direct cost of hospitalization of scrub typhus and its trend over six years.

Methods: This was a retrospective, observational, hospital based study of individuals admitted to the hospital, diagnosed with scrub typhus over six years, from January 2013 to December 2018. The potential out of pocket expenditure was evaluated.

Results: A total of 198 patients were included in the study. The median cost of admission (adjusted to INR 2020) for the six years (2013 to 2018) was found to be ₹ 37,026 (US $ 490) [interquartile range (IQR) 22,996-64,992]. The median cost for patients admitted to the intensive care unit (ICU) was ₹ 128,046 (US $ 1695) (IQR 71,575-201,171), while the cost for patients admitted to the ward-alone was ₹ 33,232 (US $ 440) (IQR 19,609-45,373). The multivariable analysis showed that ARDS and SOFA score were the independent predictors of ICU admission.

Interpretation & Conclusions: Hospitalisation for scrub typhus is associated with a substantial healthcare expense. The predictors of increased cost were the presence of acute respiratory distress syndrome (ARDS), shock, increasing sequential organ failure assessment (SOFA) score and duration of hospital stay.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466492PMC
http://dx.doi.org/10.4103/ijmr.IJMR_3917_20DOI Listing

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