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| http://dx.doi.org/10.1007/s12325-023-02626-7 | DOI Listing |
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Estimating Palatal and Pharyngeal Muscle Contraction in Hindi Syllable Pronunciation using Computational Modeling.
Indian J Plast Surg
December 2024
Department of Radiodiagnosis, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Article Synopsis
- Speech functions impacted by cleft palate involve complex sound production from various organs, and while traditional evaluations post-surgery are subjective, this study aims to provide objective assessments by measuring muscle contractions during speech.
- A healthy volunteer underwent dynamic MRI while pronouncing Hindi syllables, allowing researchers to create 3D models of the palate and pharynx, then analyze muscle contractions using a finite element model for different sounds.
- Results showed varying contraction levels for the palate and pharyngeal wall with different syllables, with the highest contractions for the syllable /k/ and the potential to use this data to quantify speech issues and evaluate surgical effectiveness in larger populations.
Management of Midface Deficiency in Syndromic Craniosynostosis with Lefort III Distraction Osteogenesis, Outcomes, and Pitfalls.
J Maxillofac Oral Surg
December 2024
104, Oral and Maxillofacial Surgery, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research Chandigarh, Chandigarh, 160012 India.
Background: Syndromic craniosynostosis is characterized by premature fusion of cranial sutures resulting in midface deficiency. Lefort III Distraction Osteogenesis (DO) has emerged as an effective surgical intervention for addressing this complex condition. This case series outlines the outcomes, encountered difficulties, and insights gained through the utilization of Lefort III Distraction Osteogenesis (DO).
View Article and Find Full Text PDFFirst Branchial Cleft Anomaly Mimicking Cholesteatoma: A Pediatric Case Study and Surgical Approach.
Am J Case Rep
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Department of Otorhinolaryngology-Head and Neck Surgery, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
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- First branchial cleft anomalies (FBCAs) are rare congenital disorders that can cause variable symptoms and complex anatomical issues, often misdiagnosed as other conditions like cholesteatoma.
- A 4-year-old girl presented with a painless mass in her left ear, leading to a thorough diagnostic process involving multiple imaging techniques that confirmed an FBCA.
- Surgical intervention to resect the fistula was successful, with no postoperative complications or recurrence, emphasizing the need for precise diagnosis and treatment in such cases.
The role of FGF15/FGF19 in the development of the central nervous system, eyes and inner ears in vertebrates.
Tissue Cell
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Área de Biología Celular, Facultad de Ciencias, Universidad de Extremadura, Avda. de Elvas s/n, Badajoz 06071, Spain.
Fibroblast growth factor 19 (FGF19), and its rodent ortholog FGF15, is a member of a FGF subfamily directly involved in metabolism, acting in an endocrine way. During embryonic development, FGF15/FGF19 also functions as a paracrine or autocrine factor, regulating key events in a large number of organs. In this sense, the Fgf15/Fgf19 genes control the correct development of the brain, eye, inner ear, heart, pharyngeal pouches, tail bud and limbs, among other organs, as well as muscle growth in adulthood.
View Article and Find Full Text PDFMultilevel-Single Stage-Functional Rhinoplasty & BRP (Barb Reposition Palatoplasty) in Surgical Management of Primary Snorers, UARS and Mild OSA.
Indian J Otolaryngol Head Neck Surg
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Inamdar Multispecialty Hosp Pune, Ghaisas Ent Hospital, Pune, India.
Obstructive sleep apnoea syndrome (OSA) is a multi-factorial disorder, with quite complex endotypes, consisting of anatomical and non-anatomical pathophysiological factors. Continuous positive airway pressure (CPAP) is recognized as the first-line standard treatment for OSA, whereas upper airway (UA) surgery is often recommended for treating mild OSA patients who have refused or cannot tolerate CPAP, mild and primary snorers. The main results achievable by the surgery are UA expansion, and/or stabilization, and/or removal of the obstructive tissue to different UA levels.
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