Introduction: Human teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human DMP1.
Materials And Methods: The DMP1 gene sequence was prepared and cloned by transfection of human 293 cells.
Results: The recombinant DMP1 was purified and characterized.
Conclusion: The results suggested its future use in dental tissue regeneration and tissue engineering.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10373089 | PMC |
| http://dx.doi.org/10.1016/j.sdentj.2023.05.006 | DOI Listing |
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