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Advances in adhesion of microneedles for bioengineering.
J Mater Chem B
January 2025
School of Chemistry and Biological Engineering, Beijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, University of Science and Technology Beijing, Beijing 100083, P. R. China.
Microneedles have provided promising platforms in various fields thanks to their safety, painlessness, minimal invasiveness and ease of operation. The excellent adhesion of microneedles is the key characteristic to achieve long-term and comfortable treatment. However, a complex environment, such as the roughness of skin, various bodily fluids , and the movement of the body, presents great challenges to the adhesion characteristics of microneedles.
View Article and Find Full Text PDFBorate ester-crosslinked polysaccharide hydrogel reinforced by proanthocyanidins for oral ulcer therapy.
Colloids Surf B Biointerfaces
January 2025
Jilin Provincial Key Laboratory of Oral Biomedical Engineering, Hospital of Stomatology, Jilin University, Changchun, China; Department of Periodontology, Hospital of Stomatology, Jilin University, Changchun, China. Electronic address:
Oral ulcers are prone to recurrence and often complicated by bacterial infections. Currently, antibiotics, glucocorticoids, and anesthetics are commonly employed in clinical practice to alleviate symptoms. However, these medications exhibit limited retention in the moist and dynamic environment of the oral cavity, and their long-term use may lead to various side effects or drug resistance.
View Article and Find Full Text PDFStructured Liquid--Liquid Emulsion Stabilized by Surface-Engineered Liquid Metal Droplets as "Mutant" Pickering Emulsifiers.
ACS Appl Mater Interfaces
January 2025
Department of Chemical Engineering, Myongji University, Yongin 17058, Republic of Korea.
Liquid metals (LMs), i.e., metals and alloys that exist in a liquid state at room temperature, have recently attracted considerable attention owing to their electronic and rheological properties useful in various cutting-edge technologies.
View Article and Find Full Text PDFHigh-Conductivity, Self-Healing, and Adhesive Ionic Hydrogels for Health Monitoring and Human-Machine Interactions Under Extreme Cold Conditions.
Adv Sci (Weinh)
January 2025
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
Ionic conductive hydrogels (ICHs) are emerging as key materials for advanced human-machine interactions and health monitoring systems due to their unique combination of flexibility, biocompatibility, and electrical conductivity. However, a major challenge remains in developing ICHs that simultaneously exhibit high ionic conductivity, self-healing, and strong adhesion, particularly under extreme low-temperature conditions. In this study, a novel ICH composed of sulfobetaine methacrylate, methacrylic acid, TEMPO-oxidized cellulose nanofibers, sodium alginate, and lithium chloride is presented.
View Article and Find Full Text PDFMedial orbitofrontal cortex structure, function, and cognition associates with weight loss for laparoscopic sleeve gastrectomy.
Obesity (Silver Spring)
February 2025
Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Objective: The objective of this study was to investigate underlying mechanisms of long-term effective weight loss after laparoscopic sleeve gastrectomy (LSG) and effects on the medial orbitofrontal cortex (mOFC) and cognition.
Methods: A total of 18 individuals with obesity (BMI ≥ 30 kg/m) underwent LSG. Clinical data, cognitive scores, and brain magnetic resonance imaging scans were evaluated before LSG and 12 months after LSG.
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