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Pattern analysis for the diagnosis of inflammatory skin lesions in domestic animals: An overview. | LitMetric

AI Article Synopsis

  • Pattern analysis of inflammatory skin diseases provides a systematic approach for diagnosing skin conditions, first introduced in human dermatopathology in the 1970s but later adopted primarily by veterinary pathologists for animals.
  • This method has helped identify new skin diseases, especially in dogs and cats, by linking the inflammatory patterns to underlying disease mechanisms.
  • While newer techniques like molecular analysis and image informatics are emerging, traditional light microscopy of tissue samples remains crucial for routine dermatopathology diagnosis in both human and veterinary fields.

Article Abstract

Pattern analysis of inflammatory skin diseases is a technique that offers a systematic approach to the histologic diagnosis of skin diseases. First introduced to human dermatopathology in the 1970s, it was widely adopted by veterinary pathologists for the histologic diagnosis of skin diseases in animals. As the inflammatory pattern reflects, to varying extents, aspects of the underlying disease pathogenesis, its use has contributed to the recognition of novel skin diseases in domestic animals, particularly in dogs and cats. Alternative diagnostic approaches used in human dermatopathology, such as "tissue-reaction pattern" and a purely "anatomic approach" have not been as widely used in veterinary pathology. However, veterinary pathologists often combine pattern analysis with anatomic and etiologic factors. This overview outlines the technique, introduces the patterns, and discusses advantages and limitations of pattern analysis in veterinary diagnostic dermatopathology. While molecular analytic techniques and image informatics will undoubtedly prove to be revolutionary in many areas of diagnostic pathology, it is recognized in both human and veterinary arenas that the light microscopic interpretation of hematoxylin and eosin-stained tissue sections will remain the mainstay of routine dermatopathology diagnosis for the foreseeable future.

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Source
http://dx.doi.org/10.1177/03009858231189456DOI Listing

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