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Markers of Oxidative Stress in Patients with Acne: A Literature Review. | LitMetric

AI Article Synopsis

  • Acne vulgaris is a chronic skin disease linked to the pilosebaceous unit, influenced by factors like altered skin cell behavior, excess oil production, bacterial growth, and inflammation.
  • Recent studies highlight that oxidative stress (an imbalance between harmful oxidants and protective antioxidants) may play a role in acne, although this association hasn't been as widely explored compared to other skin conditions.
  • The review analyzes research from the past decade on oxidative stress markers in acne patients to offer fresh perspectives on the disease's underlying causes.

Article Abstract

Acne vulgaris is a chronic inflammatory skin disease of the pilosebaceous unit. Its pathogenesis is multifactorial and involves the overlap between four main processes: alteration of the keratinization, increased sebum production, colonization with , and inflammation. The role of oxidative stress (OS) has been intensively studied in inflammatory skin conditions such as psoriasis, vitiligo, or atopic dermatitis. However, the involvement of OS in the pathogenesis of acne is less known. The evidence accumulated over the last decade suggests that in the case of acne patients, there is an imbalance between oxidants and antioxidants. In this review, we analyzed studies that evaluated markers of OS in patients with acne, published in the last ten years, with the aim of providing new insights into the pathogenesis of acne.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10381563PMC
http://dx.doi.org/10.3390/life13071433DOI Listing

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