Ovarian cancer (OC) is the eighth most common cancer worldwide and is usually diagnosed in advanced stages. Despite many available data, no treatment results have been reviewed in Poland. This study enrolled 289 first-time patients treated between 2018 and 2021 by the Department of Oncology of the Poznań University of Medical Sciences (SKPP). The relationships among starting treatment in our centre, the type of first intervention, and the final decision were significant ( < 0.001). Patients in the SKPP group were more likely to primarily have a laparoscopy and less likely to have an exploratory laparotomy. Neoadjuvant chemotherapy (NACT) after a laparotomy was less often a final decision among SKPP patients (9% vs. 22%), in contrary to NACT after a laparoscopy (23% vs. 4%). Factors affecting the shortening of progression-free survival (PFS) were an advanced stage of the disease, a histopathological diagnosis, the type of cytoreduction, and the final decision. Significance according to the final decision was revealed for PDS vs. NACT after a laparotomy ( < 0.001) and for PDS vs. NACT after a laparoscopy ( = 0.011). Our study supports the benefits of treating ovarian cancer in an oncology centre with a high patient throughput. Further observations might also answer the question about overall survival (OS).
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http://dx.doi.org/10.3390/healthcare11142043 | DOI Listing |
Comput Biol Med
December 2024
Department of Mathematics, Abdul Wali Khan University Mardan, Mardan, KP, Pakistan. Electronic address:
The selection of the most effective surgical approach is a critical decision in major surgery. With several approaches available, it is important to select the one that will have the most beneficial effect on the patient's health. Multi criteria decision making techniques are essential for identifying the most effective surgical approach to optimize patient health.
View Article and Find Full Text PDFWorld J Surg Oncol
December 2024
Department of Hospital Infection Management and Preventive Health Care, Zhejiang Provincial People's Hospital Bijie Hospital, Bijie, 551799, China.
Introduction: Although the Tumor-Node-Metastasis (TNM) staging system is widely used for staging lung squamous cell carcinoma (LSCC), the TNM system primarily emphasizes tumor size and metastasis, without adequately considering lymph node involvement. Consequently, incorporating lymph node metastasis as an additional prognostic factor is essential for predicting outcomes in LSCC patients.
Methods: This retrospective study included patients diagnosed with LSCC between 2004 and 2018 and was based on data from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute.
Sci Rep
December 2024
Department of Occupational Health and Safety Engineering, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Due to the extensive use of explosives, the failure to identify hazards and assess risks in blasting may lead to catastrophic consequences. However, classical risk assessment approaches are limited in their ability to address ambiguity and uncertainty, as well as in assigning weights to the criteria involved in the risk assessment process. This study employs a multi-criteria decision-making system to address these limitations and assess the risks associated with blasting.
View Article and Find Full Text PDFRes Social Adm Pharm
December 2024
School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, Australia.
Background: Artificial intelligence (AI), a branch of computer science, has been of growing research interest since its introduction to healthcare disciplines in the 1970s. Research has demonstrated that the application of such technologies has allowed for greater task accuracy and efficiency in medical disciplines such as diagnostics, treatment protocols and clinical decision-making. Application in pharmacy practice is reportedly narrower in scope; with greater emphasis placed on stock management and day-to-day function optimisation than enhancing patient outcomes.
View Article and Find Full Text PDFPLoS One
December 2024
Machine Learning Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.
Many peer-review processes involve reviewers submitting their independent reviews, followed by a discussion between the reviewers of each paper. A common question among policymakers is whether the reviewers of a paper should be anonymous to each other during the discussion. We shed light on this question by conducting a randomized controlled trial at the Conference on Uncertainty in Artificial Intelligence (UAI) 2022 conference where reviewer discussions were conducted over a typed forum.
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