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The 2024 European Society of Intensive Care Medicine clinical practice guideline provide clinicians with evidence-based recommendations on intravenous fluid in critically ill adults across a range of common conditions. These guidelines aim to improve the practices of fluid therapy by adopting a global perspective that considers both clinical efficacy and resource utilization in diverse healthcare settings. The guidelines address three key questions: (1) albumin versus crystalloids, (2) balanced crystalloids versus isotonic saline, and (3) small-volume hypertonic solutions versus isotonic crystalloids.
View Article and Find Full Text PDFEvaluating the accuracy of impaired skin integrity in critically ill patients: Key characteristics and clinical implications.
Int J Nurs Knowl
January 2025
Graduate Program in Nursing, Federal University of Ceará, Fortaleza, Brazil.
Objective: To evaluate the accuracy of the defining characteristics of the nursing diagnosis Impaired skin integrity (00046) in patients admitted to intensive care units (ICUs).
Methods: A cross-sectional diagnostic accuracy study was conducted with 105 adult patients admitted to an ICU. A latent class model with random effects was used to test the sensitivity and specificity of the defining characteristics investigated.
Revolutionising oral organoids with artificial intelligence.
Biomater Transl
November 2024
Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong Special Administrative Region, China.
The convergence of organoid technology and artificial intelligence (AI) is poised to revolutionise oral healthcare. Organoids - three-dimensional structures derived from human tissues - offer invaluable insights into the complex biology of diseases, allowing researchers to effectively study disease mechanisms and test therapeutic interventions in environments that closely mimic in vivo conditions. In this review, we first present the historical development of organoids and delve into the current types of oral organoids, focusing on their use in disease models, regeneration and microbiome intervention.
View Article and Find Full Text PDFUnderstanding Parental Perspectives on Childhood Hearing Impairment and Timely Interventions.
Cureus
January 2025
College of Medicine, Department of Otolaryngology - Head and Neck Surgery, University of Jeddah, Jeddah, SAU.
Objectives: Hearing impairment during childhood is a widespread health issue. Prompt recognition and timely intervention are vital for the advancement of language skills. Insufficient parental knowledge can lead to a delay in diagnosing and treating a condition, which can have a negative impact on academic performance.
View Article and Find Full Text PDFA Systematic Review of Research on Guided Access Cavity Preparation Endodontic Treatment: Dentin Preservation Perspectives.
Clin Cosmet Investig Dent
January 2025
Faculty of Mechanical and Aerospace Engineering, Institut Teknologi Bandung, Bandung, West Java, Indonesia.
Purpose: Guided access cavity preparation (GACP) is an endodontic procedure utilizing stents, guide sleeves, or dynamic guides to facilitate the proper formation of access cavities. This paper aims to evaluate the significance of research on guided access cavity preparation in endodontic treatment concerning dentin preservation. In the context of dentin preservation, this paper provides a thorough scoping review of a variety of methodologies for evaluating the accuracy of guided access cavity preparation.
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