The nanofiltration performance of three commercial membranes was analyzed by the Steric Pore Model (SPM) and the extended Nernst-Planck diffusion equation inside membrane pores. The model was completed with the equation to predict the concentration polarization, and the mass transfer coefficient was determined by considering the presence of a feed spacer. The model parameters that characterized the performance of the membrane were the hydrodynamic coefficient, which accounts for the possible variations in solute size and membrane pore radius, the effective membrane thickness, and the water permeability coefficient. All experiments were conducted at fixed feed pH of 6. The rejections of uncharged solutes (glucose for membranes with a high molecular weight cut-off (MWCO) and glycerol and ethylene glycol for membranes with a low MWCO) allowed the model parameters to be determined. We found that glycerol and ethylene glycol overestimate the membrane pore radius due to their ability to interact with the membrane matrix. Therefore, the rejection of glycine as a small amino acid was explored to characterize the membranes with low MWCO since these molecules do not interact with the membrane matrix and have an almost zero charge at pH values between 4.5 and 6.5. Based on the experimental rejections, it was stated that glucose and glycine could be separated by these membranes operating in continuous diafiltration mode.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10384295 | PMC |
| http://dx.doi.org/10.3390/membranes13070631 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Joint exploration of network pharmacology and metabolomics on the effects of traditional Chinese medicine compounds in weaned yaks.
Front Vet Sci
January 2025
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Introduction: Chinese herbal medicines are relatively inexpensive and have fewer side effects, making them an effective option for improving health and treating diseases. As a result, they have gained more attention in recent years. The weaning period is a critical stage in the life of yaks, often inducing stress in calves.
View Article and Find Full Text PDFThe immune landscape of fetal chorionic villous tissue in term placenta.
Front Immunol
January 2025
Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky, Lexington, KY, United States.
Introduction: The immune compartment within fetal chorionic villi is comprised of fetal Hofbauer cells (HBC) and invading placenta-associated maternal monocytes and macrophages (PAMM). Recent studies have characterized the transcriptional profile of the first trimester (T1) placenta; however, the phenotypic and functional diversity of chorionic villous immune cells at term (T3) remain poorly understood.
Methods: To address this knowledge gap, immune cells from human chorionic villous tissues obtained from full-term, uncomplicated pregnancies were deeply phenotyped using a combination of flow cytometry, single-cell RNA sequencing (scRNA-seq, CITE-seq) and chromatin accessibility profiling (snATAC-seq).
Golgi protein 73: charting new territories in diagnosing significant fibrosis in MASLD: a prospective cross-sectional study.
Front Endocrinol (Lausanne)
January 2025
Department of Gastroenterology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Objectives: To explore the correlation between serum Golgi protein 73 (GP73) levels and the degree of fibrosis in Metabolic dysfunction associated steatotic liver disease (MASLD); to establish a non-invasive diagnostic algorithm based on serum GP73 and liver elasticity.
Methods: This is a prospective cross-sectional study, including 228 patients diagnosed with MASLD from May 2018 to January 2024 at two tertiary hospitals. Clinical data and hepatic pathological features and the correlation between serum GP73 and liver fibrosis were assessed.
Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology.
Front Mol Biosci
January 2025
Department of Agricultural and Food Sciences (DISTAL), University of Bologna, Cesena, Italy.
Introduction: Current intestinal models lack the mechanical forces present in the physiological environment, limiting their reliability for nanotoxicology studies. Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating orbital mechanical stimulation to better replicate intestinal conditions and investigate nanoparticle interactions.
Methods: We established co-cultures under static and dynamic conditions, evaluating their development through multiple approaches including barrier integrity measurements, gene expression analysis, and confocal microscopy.
VV-ECMO adjuvant therapy for complicated with H1N1 infection: a case report.
Front Med (Lausanne)
January 2025
Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Clinical Research Center for Critical Care Medicine, Guangxi, China.
Background: Leptospirosis is an acute infectious disease that occurs by infection, progresses rapidly, and has a high mortality rate, with an estimated 1.2 million new cases and nearly 59,000 deaths each year. Due to its diverse clinical manifestations, diagnosis is often delayed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!