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http://dx.doi.org/10.1021/acsnano.3c06667 | DOI Listing |
Redox Biol
December 2024
Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea; School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address:
The dynamic equilibrium between acetylation and deacetylation is vital for cellular homeostasis. Parkinson's disease (PD), a neurodegenerative disorder marked by α-synuclein (α-syn) accumulation and dopaminergic neuron loss in the substantia nigra, is associated with a disruption of this balance. Therefore, correcting this imbalance with histone deacetylase (HDAC) inhibitors represents a promising treatment strategy for PD.
View Article and Find Full Text PDFArch Pharm (Weinheim)
January 2025
Pharmaceutical Technology Department, Faculty of Pharmacy, Misr International University (MIU), Cairo, Egypt.
Nanoscale
December 2024
Chongqing Research Center for Pharmaceutical Engineering, Chongqing Medical University, Chongqing 400016, China.
Pharmaceutics
October 2024
Department of Pathophysiology and Pharmacology, Institute of Cellular Biology and Pathology "Nicolae Simionescu" of the Romanian Academy, 8 B.P. Hasdeu Street, 050568 Bucharest, Romania.
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