Objective: We investigated the usefulness of 2D-perfusion analysis for the evaluation of cerebral blood flow in unilateral cervical internal carotid artery stenosis.
Methods: We conducted a 2D-perfusion analysis during cerebral angiography and I-iodoamphetamine (IMP) single photon emission computed tomography (SPECT) for unilateral cervical internal carotid artery stenosis without contralateral stenosis. The relationship between the ratio of the lesion side to the normal side in the parameters obtained by 2D-perfusion and the value calculated by stereotactic extraction estimation (SEE) analysis of SPECT was statistically examined.
Results: The ratios of the lesion side to the normal side regarding the peak arrival time (AT; time to peak [TTP]) of the contrast agent and the mean filling time (mean transit time [MTT]) of the contrast agent in 2D-perfusion significantly correlated with the area of Stage II and increase ratio (I.R) ≤30% in the SEE analysis (p = 0.002, 0.003).
Conclusion: 2D-perfusion analysis can be used to estimate the extent of impaired cerebrovascular reserve (CVR) area in unilateral internal carotid artery stenosis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370787 | PMC |
| http://dx.doi.org/10.5797/jnet.oa.2020-0132 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Construction of a Prognostic Nomogram for Major Amputation Within 30 Days Postrevascularization in Patients With Acute Lower Limb Ischemia Based on 2D Perfusion Parameters.
J Endovasc Ther
August 2024
Department of Interventional Radiology and Vascular Surgery, The First Affiliated Hospital, Jinan University, Guangzhou, China.
Purpose: The purpose of the study is to develop a prediction model for major amputation (MA) within 30 days after arterial revascularization in patients with acute lower limb ischemia (ALLI) using 2-dimensional (2D) perfusion imaging parameters.
Materials And Methods: A retrospective study was performed in ALLI patients undergoing arterial revascularization between October 2015 and May 2022. Patients were randomly assigned into training and validation cohorts in a ratio of 7:3.
Multimodal real-time imaging with laser speckle contrast and fluorescent contrast.
Photodiagnosis Photodyn Ther
February 2024
Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, South Korea; Department of Biomedical Engineering, Pukyong National University, Busan 48513, South Korea. Electronic address:
Introduction: Laser speckle contrast imaging (LSCI) can achieve real-time 2D perfusion maps non-invasively. However, LSCI is still difficult to use in general clinical applications because of movement sensitivity and limitations in blood flow analysis. To overcome this, fluorescence imaging (FI) is combined with LSCI using a light source with a wavelength of 785 nm in near-infrared (NIR) region and validates to visualize real-time blood perfusion.
View Article and Find Full Text PDFDSA-Based 2D Perfusion Measurements in Delayed Cerebral Ischemia to Estimate the Clinical Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage: A Technical Feasibility Study.
J Clin Med
June 2023
Department of Neuroradiology, University Medical Centre, Johannes Gutenberg University of Mainz, 55131 Mainz, Germany.
(1) Background: To predict clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH) and delayed cerebral ischemia (DCI) by assessment of the cerebral perfusion using a 2D perfusion angiography (2DPA) time-contrast agent (CA) concentration model. (2) Methods: Digital subtraction angiography (DSA) data sets of n = 26 subjects were acquired and post-processed focusing on changes in contrast density using a time-concentration model at three time points: (i) initial presentation with SAH (T0); (ii) vasospasm-associated acute clinical impairment (T1); and (iii) directly after endovascular treatment (T2) of SAH-associated large vessel vasospasm (LVV), which resulted in n = 78 data sets. Maximum slope (MS in SI/ms), time-to-peak (TTP in ms), and maximum amplitude of a CA bolus (dSI) were measured in brain parenchyma using regions of interest (ROIs).
View Article and Find Full Text PDF2D perfusion angiography: an alternative method to evaluate endovascular intervention for acute lower limb ischemia.
BMC Cardiovasc Disord
December 2022
Department of Interventional Radiology and Vascular Surgery, The First Affiliated Hospital of Jinan University, No. 613 West Huangpu Avenue, Guangzhou, 510630, China.
Article Synopsis
- The study assesses the effectiveness of 2D perfusion angiography in evaluating outcomes of endovascular interventions for acute limb ischemia (ALI), which is challenging due to difficulties in measuring limb blood flow.
- An analysis of 47 ALI patients showed significant improvements in transcutaneous oxygen (TcPO2) levels and ankle-brachial index (ABI) after treatment, indicating enhanced limb perfusion.
- Results revealed that the time to peak (TTP) for blood flow improved post-intervention, with faster TTP in the knee and ankle areas compared to pre-treatment, particularly among patients who responded positively to the intervention.
2D-perfusion angiography for intra-procedural endovascular treatment response assessment in chronic mesenteric ischemia: a feasibility study.
BMC Med Imaging
May 2022
Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
Background: Endovascular revascularization has become the first-line treatment of chronic mesenteric ischemia (CMI). The qualitative visual analysis of digital subtraction angiography (DSA) is dependent on observer experience and prone to interpretation errors. We evaluate the feasibility of 2D-Perfusion Angiography (2D-PA) for objective, quantitative treatment response assessment in CMI.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!