AI Article Synopsis
- * Combining arsenic trioxide with other treatments like anticancer drugs, vitamins, and plant products can help mitigate these side effects and enhance therapy effectiveness.
- * The review also covers recent findings on the heart-related side effects of arsenic trioxide, aiming to improve its clinical use and safety.
Article Abstract
Arsenic trioxide is a first-line treatment drug for acute promyelocytic leukemia, which is also effective for other kinds of leukemia. Its side effects, however, limit its clinical application, especially for patients with complex leukemia symptoms. Combination therapy can effectively alleviate these problems. This review summarizes the research progress on the combination of arsenic trioxide with anticancer drugs, vitamin and vitamin analogs, plant products, and other kinds of drugs in the treatment of leukemia. Additionally, the new progress in arsenic trioxide-induced cardiotoxicity was summarized. This review aims to provide new insights for the rational clinical application of arsenic trioxide.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374529 | PMC |
| http://dx.doi.org/10.1038/s41420-023-01558-z | DOI Listing |
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