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Optimal cutoff values of intraoperative parathyroid hormone for predicting early and permanent hypoparathyroidism after total thyroidectomy.
Langenbecks Arch Surg
January 2025
Unidad de Cirugía Endocrina, Hospital Universitari de Bellvitge, C/ Feixa Llarga s/n, L'Hospitalet de Llobregat, Barcelona, E-0897, Spain.
Purpose: Measurement of intraoperative intact parathyroid hormone (ioPTH) levels is a reliable predictor of postsurgical hypocalcemia. We assessed the optimal cutoff values of ioPTH decline for predicting postoperative early and permanent hypoparathyroidism.
Methods: This was a retrospective study of a prospectively maintained database of patients undergoing thyroid surgery in a tertiary care hospital in L'Hospitalet de Llobregat (Barcelona, Spain).
Case report: Relapse of intrathyroidal parathyroid carcinoma in a patient with novel variants in and genes.
Front Oncol
January 2025
Administration, Endocrinology Research Center, Moscow, Russia.
Parathyroid carcinoma (PC) is one of the rarest malignant neoplasms of the human endocrine system, with a prevalence of approximately 0.005% of all oncological diseases. Despite its indolent course, PC generally relapses in about 40%-60% of cases.
View Article and Find Full Text PDFPostoperative and permanent hypocalcemia after indocyanine green (ICG) angiography-guided total thyroidectomy and central neck dissection: A retrospective cohort study.
Surgery
January 2025
Service of Digestive and General Surgery, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Background: This study aimed to compare the rates of postoperative and permanent hypocalcemia between postthyroidectomy indocyanine green angiography and indocyanine green angiography-guided thyroidectomy performed intraoperatively for identification and preservation of the parathyroids.
Methods: We undertook a retrospective study of 2 cohorts of patients with thyroid cancer undergoing total thyroidectomy and central neck dissection. The first cohort (control group) included patients who underwent postthyroidectomy indocyanine green angiography to predict parathyroid function by scoring the degree of fluorescence (0, black; nonvascularized; 1, gray/heterogeneous: partially vascularized; and 2, white: well vascularized), and the second cohort (angiography-guided thyroidectomy) included patients undergoing initially indocyanine green angiography-guided thyroidectomy to identify the feeding vessels of the parathyroid glands followed by postthyroidectomy indocyanine green angiography.
Aptamer-Antibody Birecognized Sandwich SERRS Biosensor in Accurate and Rapid Identification of Intraoperative Parathyroid Hormone.
Anal Chem
January 2025
State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, College of Energy, Discipline of Intelligent Instrument and Equipment, Cancer Center and Department of Breast and Thyroid Surgery, Department of Ultrasound, Xiang'an Hospital of Xiamen University, School of Medicine, Laboratory Animal Center Xiamen University, Xiamen University, Xiamen 361005, China.
With the increasing incidence of thyroid cancer worldwide and the increasing demand for surgery, the risk of parathyroid injury is also increasing, which will lead to postoperative hypoparathyroidism (HP) and hypocalcemia. In order to improve the quality of life of patients after surgery, there is an urgent need to develop a novel platform that can identify the parathyroid gland immediately during surgery. The parathyroid gland promotes the increase of blood calcium concentration by secreting parathyroid hormone (PTH).
View Article and Find Full Text PDFAtypical parathyroid tumor: A rare cause of primary hyperparathyroidism in an adolescent.
Arch Argent Pediatr
January 2025
Hospital Italiano de Buenos Aires, City of Buenos Aires, Argentina.
Hyperparathyroidism is a rare entity in pediatrics. It is defined as the increased production of parathyroid hormone. It may be due to a primary defect of the parathyroid glands (primary hyperparathyroidism) or to a compensatory parathyroid hormone production to correct hypocalcemia states of various origins (secondary hyperparathyroidism).
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