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Exposed weapons: A revised reconstruction of the facial anatomy and life appearance of the saber-toothed cat Megantereon (Felidae, Machairodontinae).
Anat Rec (Hoboken)
December 2024
Departamento de Paleobiología, Museo Nacional de Ciencias Naturales-CSIC, Madrid, Spain.
Megantereon was a widespread saber-toothed felid from the Pliocene and Pleistocene of the Old World and North America, but its rarity in the fossil record makes it complicated to restore its life appearance. Lack of complete specimens makes it necessary to combine information from fossils of different individuals to reconstruct their facial anatomy. In this work, we combine the analysis of skulls and mandibles of Megantereon from various fossil sites with the study of extant carnivorans through dissection, 3D scans, and the observation of live individuals.
View Article and Find Full Text PDFEffect of cavity designs on instrumentation, obturation and fracture resistance of mandibular first premolars with Vertucci V canal.
J Endod
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 237# Luoyu Road, Wuhan 430079, People's Republic of China. Electronic address:
Introduction: This study aimed to assess the effect of cavity designs on instrumentation, obturation and fracture resistance for mandibular first premolars with Vertucci V canal.
Methods: Mandibular first premolars with Vertucci V canal were scanned with micro-CT. 20 teeth with moderately curved canal were prepared with conservative endodontic cavity (CEC/M) or traditional endodontic cavity (TEC/M), and 30 with severely curved canal were prepared with CEC (CEC/S), modified CEC (MCEC/S) or TEC (TEC/S).
Microstructural Analysis of the Human Scapula: Mandibular Bone Tissue Engineering Perspectives.
J Funct Biomater
December 2024
Biotechnology Research Institute, Samara State Medical University, 443079 Samara, Russia.
Mandibular bone defect reconstruction remains a significant challenge for surgeons worldwide. Among multiple biodegradable biopolymers, allogeneic bone scaffolds derived from human sources have been used as an alternative to autologous bone grafts, providing optimal conditions for cell recruitment, adhesion, and proliferation and demonstrating significant osteogenic properties. This study aims to investigate the bone microstructure of the human scapula as a source for allogeneic bone scaffold fabrication for mandibular tissue engineering purposes.
View Article and Find Full Text PDFFibula flap reconstruction for maxillary stage 3 medication-related osteonecrosis of the jaw from recipient and donor site perspectives: a preliminary single-center study.
BMC Oral Health
December 2024
Department of Oral and Maxillofacial Surgery, Fujian Medical University Union Hospital, Fuzhou, China.
Background: While the surgical treatment of mandibular stage 3 medication-related osteonecrosis of the jaw (MRONJ) is well-documented, research on maxillary stage 3 MRONJ is limited. Antiresorptive medications can induce MRONJ and atypical femoral fracture (AFF), but their impact on the feasibility of using fibula flaps for reconstruction remains controversial. This study aimed to assess the surgical outcomes and functional recovery of fibula flap reconstruction for maxillary stage 3 MRONJ, considering both recipient and donor site outcomes.
View Article and Find Full Text PDFMandibular bone defect healing using polylactic acid-nano-hydroxyapatite-gelatin scaffold loaded with hesperidin and dental pulp stem cells in rat.
Tissue Cell
December 2024
Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Natural Sciences, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan. Electronic address:
Addressing mandibular defects poses a significant challenge in maxillofacial surgery. Recent advancements have led to the development of various biomimetic composite scaffolds aimed at facilitating mandibular defect reconstruction. This study aimed to assess the regenerative potential of a novel composite scaffold consisting of polylactic acid (PLA), hydroxyapatite nanoparticles (n-HA), gelatin, hesperidin, and human dental pulp stem cells (DPSCs) in a rat model of mandibular bone defect.
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