AI Article Synopsis

  • Burkitt's lymphoma is typically found in the ileum but is rarely seen in the duodenum, needing a histological examination for diagnosis and showing a characteristic "starry sky" appearance with positive tumor markers.
  • A case presented involves a child with recurrent vomiting and weight loss, where imaging revealed a duodenal mass leading to obstruction, ultimately diagnosed as Burkitt's lymphoma after endoscopic biopsies.
  • Although rare, Burkitt's lymphoma should be included in the differential diagnosis for duodenal issues to enable timely treatment, as it responds well to chemotherapy if no adverse prognostic factors are present.

Article Abstract

Introduction And Importance: The presence of Burkitt's lymphoma in the duodenum is very rare, as this lymphoma is most commonly found at the end of the ileum, as it contains a high proportion of lymphoid tissue, spreads rapidly, and is aggressive. Primary diagnosis by histological examination. It gives a starry sky view with positive for tumor markers.

Case Presentation: We reported a child suffering from recurrent vomiting with weight loss, and a radiological examination revealed the presence of a mass in the duodenum causing obstruction there. Upper gastrointestinal endoscopy was performed, and biopsies were obtained for histologic examination. Burkitt's lymphoma was then diagnosed, palliative surgery was performed, and appropriate chemotherapy was subsequently applied.

Clinical Discussion: Burkitt's lymphoma is rare in the duodenum. However, it should be considered in the differential diagnosis of duodenal problems to allow early diagnosis and treatment.

Conclusion: Burkitt's lymphoma is diagnosed by histologic examination and is very aggressive. However, it is highly responsive to chemotherapy in the absence of poor prognostic factors.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413052PMC
http://dx.doi.org/10.1016/j.ijscr.2023.108525DOI Listing

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