Most El Niño events occur sporadically and peak in a single winter, whereas La Niña tends to develop after an El Niño and last for two years or longer. Relative to single-year La Niña, consecutive La Niña features meridionally broader easterly winds and hence a slower heat recharge of the equatorial Pacific, enabling the cold anomalies to persist, exerting prolonged impacts on global climate, ecosystems and agriculture. Future changes to multi-year-long La Niña events remain unknown. Here, using climate models under future greenhouse-gas forcings, we find an increased frequency of consecutive La Niña ranging from 19 ± 11% in a low-emission scenario to 33 ± 13% in a high-emission scenario, supported by an inter-model consensus stronger in higher-emission scenarios. Under greenhouse warming, a mean-state warming maximum in the subtropical northeastern Pacific enhances the regional thermodynamic response to perturbations, generating anomalous easterlies that are further northward than in the twentieth century in response to El Niño warm anomalies. The sensitivity of the northward-broadened anomaly pattern is further increased by a warming maximum in the equatorial eastern Pacific. The slower heat recharge associated with the northward-broadened easterly anomalies facilitates the cold anomalies of the first-year La Niña to persist into a second-year La Niña. Thus, climate extremes as seen during historical consecutive La Niña episodes probably occur more frequently in the twenty-first century.
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http://dx.doi.org/10.1038/s41586-023-06236-9 | DOI Listing |
Psychol Addict Behav
December 2024
College of Health and Human Development, Pennsylvania State University.
Objective: Simultaneous use of alcohol and cannabis is prevalent among young adults and associated with heightened risk for harms. Individuals who engage in simultaneous use report a variety of types of use occasions and risk factors driving use occasions are unique and dynamic in nature. Intervention content may thus need to adapt to address differences across occasions.
View Article and Find Full Text PDFBehav Sleep Med
January 2025
Center for Sleep and Circadian Science, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
J Consult Clin Psychol
August 2024
School of Social Work, University at Buffalo.
Objective: Negative affect and affect variability figure prominently in models of addictive behaviors but are not without controversy. Negative affect variability may better capture a mechanism of behavior change in alcohol use disorder (AUD) treatment because it contains information about affect regulation, a common clinical target. The aims of this study are to examine the change in: (a) trajectory of negative affect variability, (b) association of negative affect variability and abstinence, and (c) association of negative affect variability and heavy drinking during AUD treatment.
View Article and Find Full Text PDFTransl Psychiatry
September 2024
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Toxics
August 2024
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Opioid-related deaths are attributed to overdoses, and fentanyl overdose has been on the rise in many parts of the world, including the USA. Glutamate transporter 1 (GLT-1) has been identified as a therapeutic target in several preclinical models of substance use disorders, and β-lactams effectively enhance its expression and function. In the current study, we characterized the metabolomic profile of the nucleus accumbens (NAc) in fentanyl-overdose mouse models, and we evaluated the protective effects of the functional enhancement of GLT-1 using β-lactams, ceftriaxone, and MC-100093.
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