The authors report a case of Wegener's granulomatosis, whose initial manifestation was an isolated endobronchial stenosis. In connection with this observation, it calls to mind, within the scope of the pulmonary granulomas (in view of such a rare clinical presentation) the difficulties of differential diagnosis, in particular with bronchocentric granulomatosis, and stresses the need for pulmonary histological examination to open lung biopsy.
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Heliyon
January 2025
Université de Reims Champagne-Ardenne, INSERM, P3Cell UMR-S1250, Reims, France.
Hedgehog (HH) pathway is involved in pulmonary development and lung homeostasis. It orchestrates airway epithelial cell (AEC) differentiation and contributes to respiratory pathogenesis. The core elements Gli2, Smo, and Shh were found altered in the bronchial epithelium of patients with chronic obstructive pulmonary disease (COPD).
View Article and Find Full Text PDFObjective: To assess the Knowledge, Attitudes and Practices (KAP) among healthcare professionals in managing patients with coexisting hypertension and bronchial asthma.
Design: A cross-sectional survey. The reporting of this study followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist.
Cureus
December 2024
College of Nursing, Muslim Educational Society (MES) Medical College Hospital, Perinthalmanna, IND.
Introduction: Asthma is a chronic lung disease that negatively affects children's quality of life (QoL). Improving QoL is a key outcome in managing children with asthma.
Objectives: The objective of the study was to evaluate the effectiveness of a comprehensive interventional package on QoL among asthmatic children attending an asthma clinic at a selected hospital.
Front Public Health
January 2025
College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
Background: Bronchial asthma is a global health problem in particular a respiratory condition characterized by broncho spasms that negatively affect the quality of life (QOL) of children. However, there is a paucity of data regarding the health-related quality of life of asthma in children in Ethiopia, and the study area.
Objective: The objective of this study was to assess the health-related quality of life among asthmatic children aged 7-17 in selected hospitals in Addis Ababa, Ethiopia.
Sci Rep
January 2025
Department of Environmental Medicine, University of Rochester Medical Center, Rochester, NY, US.
Little is known about how exclusive e-cigarette use affects exosomal microRNA (miRNA) expression, which is crucial in inflammation and disease processes like cancer. We compared exosomal miRNA profiles between exclusive e-cigarette users and non-users. We used plasma samples from 15 exclusive e-cigarette users and 15 non-users from the Population Assessment of Tobacco and Health (PATH) Wave 1 study (2013-2014) and sequenced miRNAs with Illumina NextSeq 500/550.
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