Purpose: To establish a parameter-based grading system for evaluating bladder trabeculation (BT).
Materials And Methods: A retrospective analysis was conducted on children diagnosed with posterior urethral valve (PUV) or neurogenic bladder (NB) who underwent voiding cystourethrogram (VCUG), urodynamic testing, and urological ultrasonography between January 2016 and October 2022. Cases involving urologic surgery, secondary bladder pathology, and an interval of more than 12 months between examinations were excluded. A parameter named Bladder Dispersion (BD) was calculated through fluoroscopic images, and the grading system was developed as follows: BD < 40 (Grade 0), 40 ≤ BD < 60 (Grade 1), 60 ≤ BD < 90 (Grade 2), BD ≥ 90 (Grade 3). Grades 0-1 were classified as low-risk group, while grades 2-3 were classified as high-risk group. Analysis of variance, Kruskal-Wallis test, and Chi-square test were performed to compare urodynamic results and complications across different grades and groups.
Results: A total of 74 patients were eligible to participate, which included 46 boys (62.2%) and 28 girls (37.8%), the mean age was 75.18 ± 48.39 months. Among them, 11 (14.9%) were PUV, 50 (67.6%) were NB, and 13 (17.5%) were PUV and NB. Significant differences were observed in maximum detrusor pressure, post-void residual urine ratio, and compliance among grades 0-3. Severe hydronephrosis and histories of urinary tract infection were more prevalent in the high-risk group.
Conclusion: A reliable grading system with objective standards was proposed which could aid in the assessment of BT severity.
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http://dx.doi.org/10.1007/s00345-023-04527-4 | DOI Listing |
Infectious Agents and Cancer journal has recently launched a new collection of papers about "Point-of-Care (POC) for HPV-related genital cancers" putting together some interesting works on the accuracy of HPV tests for screening. This editorial initiative gave us the opportunity to reflect on the relations between accuracy measures, prevalence and characteristics of the tested population in the case of HPV-based screening. In screening test evaluation, we look at the clinical accuracy of the test as an intrinsic characteristic of the assay, which interacts with the characteristics of the population, the result being the screening performance.
View Article and Find Full Text PDFBMC Cancer
December 2024
Department of Radiation Oncology, University of California, 200 Medical Plaza Driveway, Suite #B265, Los Angeles, CA, 90025, USA.
Background: Many patients with head and neck cancer are not candidates for standard of care definitive treatments though often require palliative treatments given the frequent symptoms associated with head and neck cancer. While existing palliative radiotherapy regimens can provide adequate symptom control, they have limitations particularly with respect to local control which is becoming more important as advances in systemic therapy are improving survival. Personalized ultrafractionated stereotactic adaptive radiotherapy (PULSAR) is a novel radiotherapy regimen which leverages advances in radiotherapy treatment technology and extended interfraction intervals to enable adaptive radiotherapy and possible synergy with the immune system.
View Article and Find Full Text PDFBMC Anesthesiol
December 2024
Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Background: Intravenous administration of sufentanil during anesthesia induction induces cough (SIC), sometimes triggers a severe reaction. We wanted to investigate the inhibitory effect of low-dose esketamine on cough induced by sufentanil during the induction of general anesthesia, as well as its postoperative impact on mental status (MMSE score, RSS, and VAS-A).
Methods: A total of 256 adult patients were randomly allocated to receive either esketamine (Group EK) or normal saline (Group C).
Comput Med Imaging Graph
December 2024
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, China; Department of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, China. Electronic address:
Accurate preoperative grading of prostate cancer is crucial for assisted diagnosis. Multi-parametric magnetic resonance imaging (MRI) is a commonly used non-invasive approach, however, the interpretation of MRI images is still subject to significant subjectivity due to variations in physicians' expertise and experience. To achieve accurate, non-invasive, and efficient grading of prostate cancer, this paper proposes a deep learning method that adaptively fuses dual-view MRI images.
View Article and Find Full Text PDFJ Therm Biol
December 2024
Laboratory of Sport, Expertise and Performance (EA 7370), French National Institute of Sport (INSEP), Paris, France. Electronic address:
Introduction: The relationship between blood distribution, body temperature, and sleep/wakefulness states is still unclear. The aim of the present study is to systematically review the potential beneficial effects of bedding strategies (e.g.
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