AI Article Synopsis
- There is a strong link between sarcopenia, which is the loss of muscle mass and strength, and metabolic-associated fatty liver disease (MAFLD).
- Both conditions share similar biological processes, and their coexistence can lead to more severe health issues and increased risk of death.
- Understanding the relationship between muscle loss and liver health is crucial for early detection and treatment of these conditions, and this review highlights the need for better therapies.
Article Abstract
The current evidence indicates a strong association between sarcopenia, the loss of muscle mass and strength, and metabolic-associated fatty liver disease (MAFLD). The two entities share many common pathophysiologic mechanisms, and their coexistence may result in higher rates of morbidity and mortality. Therefore, given their increasing incidence in the modern world, there is a need for a better understanding of the liver-muscle axis for early identification of sarcopenia in patients with MAFLD and vice versa. This review aims at presenting current data regarding the correlation between sarcopenia and MAFLD, the associated comorbidities, and the need for effective therapies.
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| http://dx.doi.org/10.1016/j.ecl.2023.02.004 | DOI Listing |
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