AI Article Synopsis
- The study focuses on a metallaphotoredox catalyzed cross-coupling reaction between arylbromides (Ar-Br) and alkyl bis(catecholato)silicates (R-Si), using various analytical tools and modeling techniques.
- Researchers identified four key control parameters: concentrations of the iridium photocatalyst, nickel precatalyst, silicate, and light intensity, which affect the reaction's efficiency.
- Two distinct reaction pathways were discovered: one leads to the desired product Ar-R without side products, while the other results in the degradation of R-Si to R-H alongside the formation of Ar-R.
Article Abstract
Metallaphotoredox catalyzed cross-coupling of an arylbromide (Ar-Br) with an alkyl bis(catecholato)silicate (R-Si ) has been analyzed in depth using a continuum of analytical techniques (EPR, fluorine NMR, electrochemistry, photophysics) and modeling (micro-kinetics and DFT calculations). These studies converged on the impact of four control parameters consisting in the initial concentrations of the iridium photocatalyst ([Ir] ), nickel precatalyst ([Ni] ) and silicate ([R-Si ] ) as well as light intensity I for an efficient reaction between Ar-Br and R-Si . More precisely, two regimes were found to be possibly at play. The first one relies on an equimolar consumption of Ar-Br with R-Si smoothly leading to Ar-R, with no side-product from R-Si and a second one in which R-Si is simultaneously coupled to Ar-Br and degraded to R-H. This integrative approach could serve as a case study for the investigation of other metallaphotoredox catalysis manifolds of synthetic significance.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/chem.202301780 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!