Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways.

Colemonts-Vroninks Haaike Norman P Brendan Van Laere Sven Davison S Andrew Marcélis Lionel Casimir Georges Goyens Philippe Claes Paul De Bundel Dimitri Martens Geert Ranganath Lakshminarayan Rao Vanhaecke Tamara Gallagher James A De Kock Joery

Genes Dis

Vrije Universiteit Brussel, Liver Therapy & Evolution Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.

Published: September 2023

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363636	PMC
http://dx.doi.org/10.1016/j.gendis.2022.11.013	DOI Listing

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