Perforating Gout: Expanding the Differential for Transepidermal Elimination.

Dermatopathology (Basel)

Department of Medicine, Sunnybrook Campus, University of Toronto, 2075 Bayview Ave., Toronto, ON M4N 3N5, Canada.

Published: July 2023

Perforating dermatoses are dermatologic disorders with transepidermal elimination (TE) of dermal substances. While TE is typically associated with collagen and elastin, it can also occur as a secondary event in other processes, and it is important to keep a broad differential. We present a case of perforating tophaceous gout, which underscores the need for a thoughtful approach to perforating disorders. An updated review of recent literature is also presented.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366899PMC
http://dx.doi.org/10.3390/dermatopathology10030029DOI Listing

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