Folliculosebaceous cystic hamartoma is a cutaneous malformation composed of a cystic folliculosebaceous structure associated with mesenchymal elements, generally consisting of fibrous stroma, adipocytes and small vascular channels. We report the case of a 55-year-old female patient with a cutaneous nodule of the right nasal wing. Microscopically, the lesion showed a dilated hair follicle with multiple sebaceous glands, surrounded by a mesenchymal component composed of fibromyxoid stroma, spindle cells, mature-appearing adipocytes and collagen bundles, resembling spindle cell lipoma, associated with an additional neural component, consisting of small nerve bundles. In folliculosebaceous cystic hamartoma, the association of spindle cell lipomatous and neural components has not previously reported.
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http://dx.doi.org/10.3390/dermatopathology10030027 | DOI Listing |
Dermatol Reports
September 2024
Institute for Research in Biomedical Sciences, Faculty of Human Medicine, Ricardo Palma University, Lima.
The skin covers our body and exhibits a complex structure that is adapted to the different body areas. The scalp skin is distinctive, and the histopathological alterations in its diseases also present distinctive features. We present the clinical case of a 28-year-old female patient, with no significant medical history.
View Article and Find Full Text PDFBMJ Case Rep
October 2024
Harvard Medical School, Boston, Massachusetts, USA
Cureus
June 2024
Pathology and Laboratory Medicine, London Health Sciences Centre, London, CAN.
Dermatopathology (Basel)
December 2023
Department of Dermatology, Jena University Hospital, Friedrich Schiller University Jena, 07747 Jena, Germany.
Folliculosebaceous cystic hamartoma (FSCH) is a rare and benign form of cutaneous hamartomas. These skin lesions often lead to clinical and histopathological misdiagnosis due to their similarities to cutaneous lesions with overproduction of clustered sebaceous glands. Clinically, the lesions often present as solitary, skin-colored, pedunculated warts to cauliflower-like, exophytic papules and nodules, usually with a diameter ranging 0.
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