Paracoccidioidomycosis is a systemic mycosis found mainly in South America and is the most prevalent endemic and systemic mycosis in Brazil. The purpose of this paper was to report the case of a male patient who developed peritonitis caused by Paracoccidioides spp. Forty-eight-year-old, male patient, with type I Diabetes mellitus and chronic kidney disease who was undergoing a Continuous Ambulatory Peritoneal Dialysis (CAPD) program. After eighteen months of peritoneal dialysis, the patient developed turbidity of the peritoneal fluid and was diagnosed with peritonitis. Direct mycological examination of the peritoneal fluid revealed yeasts with morphology suggestive of Paracoccidioides spp. The patient was treated with sulfamethoxazole-trimethoprim (1,600 mg/320 mg dose/day) for 61 days, but he died because a bacterial septic shock. The diagnosis of opportunistic PCM peritonitis was later confirmed by autopsy and Paracoccidioides spp. isolation. This is the first reported case of a patient on CAPD who experienced complications due peritonitis caused by opportunistic PCM.
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http://dx.doi.org/10.1016/j.bjid.2023.102792 | DOI Listing |
Microbes Infect
November 2024
Laboratório de Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Goiás, 74690-900, Brazil. Electronic address:
Mycopathologia
November 2024
Laboratório de Investigação Médica em Micologia (LIM53), Instituto de Medicina Tropical de São Paulo, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Éneas de Carvalho Aguiar n470, Cerqueira Cézar, São Paulo, SP, 05403000, Brazil.
Background: The study of Paracoccidioides spp. faces significant challenges due to limitations inherent in the molecular biology techniques employed. Recently, new species were described whose geographical and genetic distributions were investigated.
View Article and Find Full Text PDFMicrob Genom
October 2024
Instituto de Medicina Regional (IMR), Universidad Nacional del Nordeste (UNNE), Av. Las Heras 727, (3500) Resistencia, Chaco, Argentina.
Paracoccidioidomycosis is a severe systemic endemic mycosis caused by spp. which mainly affects individuals in Latin America. Progress in genomics has been slow, as evidenced by the incomplete reference databases available.
View Article and Find Full Text PDFMicrob Pathog
November 2024
Department of Microbiology and Immunology at Federal University of Alfenas - UNIFAL, Alfenas, MG, CEP 37130-001, Brazil. Electronic address:
J Comp Pathol
October 2024
Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, São Paulo, SP 01246-000, Brazil; Laboratório de Patologia Comparada de Animais Selvagens, Departamento de Patologia, Faculdade de Meddicina Veterinária e Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP 05508-270, Brazil. Electronic address:
Paracoccidioidomycosis (PCM) is an endemic fungal disease that occurs in Latin America and primarily affects humans. The disease has been rarely documented in non-human primates. This report details a disseminated and fatal case of PCM caused by Paracoccidioides brasiliensis in a western black-handed tamarin (Saguinus niger) under human care.
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