Synthesis and Properties of 5-Azaullazines.

J Org Chem

Institute of Chemistry, University Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.

Published: August 2023

5-Azaullazines, indolizino[6,5,4,3-][1,5]naphthyridines, and their benzo-fused analogues were prepared in three steps by combination of Pd catalyzed cross-coupling reactions with Brønsted acid mediated cycloisomerisations. The reaction tolerates various substitution patterns and functional groups and proceeds in high yields. Optical and electrochemical properties of selected products were studied experimentally and by DFT calculations.

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http://dx.doi.org/10.1021/acs.joc.3c00386DOI Listing

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