5-Azaullazines, indolizino[6,5,4,3-][1,5]naphthyridines, and their benzo-fused analogues were prepared in three steps by combination of Pd catalyzed cross-coupling reactions with Brønsted acid mediated cycloisomerisations. The reaction tolerates various substitution patterns and functional groups and proceeds in high yields. Optical and electrochemical properties of selected products were studied experimentally and by DFT calculations.
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http://dx.doi.org/10.1021/acs.joc.3c00386 | DOI Listing |
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